New 'Beetlejuice Beetlejuice' Trailer Introduces Willem Dafoe, Monica Bellucci and More

The Juice is loose!

The official trailer for Beetlejuice Beetlejuice has arrived and this time around, three generations of Deetzes have to deal with the trouble-making spirit that is Beetlejuice.

On Thursday, Warner Bros. dropped a new trailer showing Michael Keaton's return to one of his most iconic roles to date alongside OG cast members Winona Ryder and Catherine O’Hara in their roles as Lydia and Delia Deetz.

Winona Ryder and Michael Keaton in 'Beetlejuice Beetlejuice'

Winona Ryder and Michael Keaton in 'Beetlejuice Beetlejuice'

Warner Bros.

"After an unexpected family tragedy, three generations of the Deetz family return home to Winter River," reads the movie's press release. "Still haunted by Beetlejuice, Lydia's life is turned upside down when her rebellious teenage daughter, Astrid, discovers the mysterious model of the town in the attic and the portal to the Afterlife is accidentally opened. With trouble brewing in both realms, it's only a matter of time until someone says Beetlejuice's name three times and the mischievous demon returns to unleash his very own brand of mayhem."

Several newcomers join the Tim Burton-directed franchise, including Jenna Ortega as Lydia's daughter, Astrid, as well as Willem Dafoe, Monica Bellucci and Justin Theroux.

Willem Dafoe in 'Beetlejuice Beetlejuice'

Willem Dafoe in 'Beetlejuice Beetlejuice'

Warner Bros.

The new trailer gives fans a first look at Dafoe's Wolf Jackson, a B-list movie actor who died and became a cop in the Afterlife; Bellucci's Delores, Beetlejuice's zombified but fabulous wife; and more familiar creatures, like the stop-motion-animated sandworm.

Monica Bellucci in 'Beetlejuice Beetlejuice'

Monica Bellucci in 'Beetlejuice Beetlejuice'

Warner Bros.

"The living, the dead. Can they co-exist? That's what we're here to find out," Lydia says.

Fans have been patiently waiting for a proper look at the sequel to the 1988 cult film since the teaser trailer was dropped in March, giving the world a first look at Keaton back in action and hinting at what's to come.

In March, ET spoke with Keaton, who dished about making his highly anticipated return.

"It took a while to get there," he said. "I didn't really think we were gonna do it and didn't want to do it, various times [in the] last few years, but it was more fun than the other one."

Despite the initial apprehension, Keaton said that the "tremendous cast" made the experience even better.

"[Tim] was really, really great -- back in his comfort zone," he added. "I could tell he was having fun. Which is really contagious, when you're around that."

Beetlejuice Beetlejuice hits theaters on Sept. 6.

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