NFL picks and predictions: Week 10

Nine weeks in, the NFL landscape has taken shape. Week 10 gives us a number of intriguing matchups -- most notably the Seattle Seahawks traveling to Foxboro for a Super Bowl 49 rematch, and the Dallas Cowboys facing another crucial test in Pittsburgh.

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We picked all of this weekend's games below. Take a gander and let us know where you disagree.

Kansas City Chiefs vs. Carolina Panthers (CAR -3)
Sunday, 1 p.m. ET


After a rocky start, Carolina is now a winner of its last two games, but now hosts a Chiefs team that seems to be gaining more and more momentum each week. KC will be in search of its fifth straight victory, and their advantage in the turnover battle should be what sets them over the edge on Sunday.

Pick: Chiefs

Denver Broncos vs. New Orleans Saints (NO -2.5)
Sunday, 1 p.m. ET

Denver's offensive struggles of late haven't been a secret, but against a defense as weak as New Orleans' even it shouldn't have issues putting up enough numbers to eke out a victory -- especially considering Denver's defense has only allowed 312 total yards per game, good for fourth-best in the league.

Pick: Broncos

Los Angeles Rams vs. New York Jets (NYJ -2)
Sunday, 1 p.m. ET

While mired in a brutal stretch of poor play, Ryan Fitzpatrick has posted a passer rating over 100 in four of his last six home games. The Jets boast the league's fourth-best rush defense, and if they limit Todd Gurley and force Case Keenum to make play's, they'll have a good chance.

Pick: Jets

Green Bay Packers vs. Tennessee Titans (GB -2.5)
Sunday, 1 p.m. ET

The Packers travel to Tennessee for the first time since 2008, fresh off a demoralizing loss to Indianapolis. The Titans have alternated wins and losses over the last several weeks, but look for them to drop a second consecutive as Green Bay rebounds with a victory.

Pick: Packers

Atlanta Falcons vs. Philadelphia Eagles (ATL -1)
Sunday, 1 p.m. ET


After having asserted themselves as one of the league's elite, Atlanta travels to Philadelphia to face an Eagles team fighting to stay on track in the NFC East. While Philly's hot start put them in a prime position to compete, nothing they've shown lately leads us to believe that they can knock off a team as well-rounded as the Falcons.

Pick: Falcons

Minnesota Vikings vs. Washington Redskins (WAS -3)
Sunday, 1 p.m. ET

In the midst of a hotly contested NFC East race, Washington hosts the Vikings, who haven't won in more than a month after a hot start. This one shapes up to be a close matchup, but we don't have enough trust in Washington's offense to surge past the Vikings D.

Pick: Vikings

Houston Texans vs. Jacksonville Jaguars (HOU -1)
Sunday, 1 p.m. ET

Houston's offense has had its fair share of struggles over the first half of the regular season, but a matchup against the Jaguars could be just what it needs to get on track. The Jags have allowed the eighth-most points per game this season with 26.9.

Pick: Texans

Chicago Bears vs. Tampa Bay Buccaneers (TB -1)
Sunday, 1 p.m. ET

The Buccaneers are fresh off getting manhandled by the Falcons in primetime in a game that Jameis Winston had to leave early due to injury. He's apparently ready to go for Week 10, and against a Bears team that's struggled all year, it's easy to see Tampa Bay taking care of business at home.

Pick: Buccaneers

Miami Dolphins vs. San Diego Chargers (SD -4)
Sunday, 4:05 p.m. ET


Winners in three of their last four, San Diego will look to remain competitive at home against a Dolphins team that's also performed better as of late. While Jay Ajayi has been stellar, we're still skeptical about Ryan Tannehill leading Miami to victory in a tough matchup.

Pick: Chargers

San Francisco 49ers vs. Arizona Cardinals (ARI -13.5)
Sunday, 4:25 p.m. ET

A two-touchdown spread is harsh, but in this particular instance, it may not be that far off. The 49ers have struggled to score all season, and against Arizona's defense, those struggles will continue.

Pick: Cardinals

Dallas Cowboys vs. Pittsburgh Steelers (PIT -2.5)
Sunday, 4:25 p.m. ET

The Cowboys face another test, traveling to Heinz Field to take on the Steelers. In his first game back from knee surgery last week, Ben Roethlisberger was noticeably rusty. If he's not at 100 percent this week, Dallas is good enough to come in and grab a win on the road.

Pick: Cowboys

Seattle Seahawks vs. New England Patriots (NE -7.5)
Sunday, 8:30 p.m. ET


A Super Bowl 49 rematch comes to Sunday Night Football this week, as the Seahawks travel to Foxboro in an attempt to do what no team has done this year: beat the Patriots with Tom Brady under center. A 7.5-point spread seems a bit excessive, but we don't think New England will have trouble handling this Seattle team at home.

Pick: Patriots

Cincinnati Bengals vs. New York Giants (NYG -2.5)
Monday, 8:30 p.m. ET

The Bengals roll into MetLife Stadium for the second time this season, with a Week 1 win agains the Jets under their belt. Since, though, Cincy has won just twice, with one of those victories coming against the Browns. With the Giants attempting a surge toward Dallas at the top of the NFC East, expect the home team to come out firing on Monday night.

Pick: Giants

Week 10 Power Rankings

NFL Power Rankings: Week 10
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NFL Power Rankings: Week 10

32. Browns (0-9)
Last Week: 32

The Browns are closing in on one calendar year since their last victory. At this point, going 0-16, and grabbing the draft's No. 1 overall pick, is probably their best course of action.

(Photo by Gregory Shamus/Getty Images)

31. 49ers (1-7)
Last Week: 31

That's seven straight losses now for San Francisco, despite a strong performance from Colin Kaepernick. His play was encouraging, but it's merely in an audition for other teams next year.

(Photo by Jason O. Watson/Getty Images)

27. Ravens (4-4)
Last Week: 25

Baltimore has dropped back to .500 after a 3-0 start, but have the benefit of playing Cleveland in Week 10. With Pittsburgh and Cincinnati struggling, the door has been left open for the Ravens to sneak into the postseason, and a win this week would put them a step ahead.

(Photo by Evan Habeeb-USA TODAY Sports via Reuters)

26. Rams (3-6)
Last Week: 23

The Rams supposedly won't turn to Jared Goff until they're out of playoff contention. Said another way: It won't be long until we get to see the No. 1 overall pick.

(Photo by Stephen Dunn/Getty Images)

23. Buccaneers (3-5)
Last Week: 21

Tampa got smoked at home in prime time by a superior team in the Falcons, and lost Jameis Winston due to injury in garbage time. Winston has practiced this week, and with a winnable game against the Bears looming, the Buccaneers will need him.

(Photo by Mark LoMoglio/Icon Sportswire via Getty Images)

22. Titans (4-5)
Last Week: 20

Tennessee continued alternating wins and losses on Sunday against a resurgent Chargers team, but posted 35 points while Marcus Mariota threw for more than 300 yards. They'll face another tough test in going against the Packers next week before a rematch with the Colts in a crucial divisional battle.

(Photo by Chris Williams/Icon Sportswire via Getty Images)

21. Colts (4-5)
Last Week: 24

The Colts' bye week comes at an inopportune time, with the team fresh off its best win of the season. Still, the victory over Green Bay was encouraging, and could be a pivotal moment of the Colts' season.

(Photo by Dylan Buell/Getty Images)

20. Panthers (3-5)
Last Week: 22

That's two straight wins now for the Panthers, but the real test comes next week, against the most quietly hot team in football: Kansas City.

(Photo by Stephen Dunn/Getty Images)

18. Redskins (4-3-1)
Last Week: 15

Washington takes on the Vikings at the best possible time, with Minnesota losing three straight and the Skins well-rested off a bye. They'll need a win to keep up with the rest of the NFC East, and there's a chance they get it.

(Photo by Alan Crowhurst/Getty Images)

17. Texans (5-3)
Last Week: 14

Houston has scored just 22 points over its last two games, but will go up against a Jacksonville team in Week 10 that ranks 25th in points allowed per game.

(Photo by Ken Murray/Icon Sportswire via Getty Images)

16. Eagles (4-4)
Last Week: 11

The Eagles have now lost four of their last five, and now take on a Falcons team that's won six of eight since a Week 1 loss. The Eagles need a win to stay on pace in the division, but each week Atlanta appears to be a more and more formidable opponent.

(Photo by Jeff Zelevansky/Getty Images)

15. Chargers (4-5)
Last Week: 18

The Chargers have no won three of their last four, and host the Dolphins before a Week 11 bye. Melvin Gordon, who now leads the NFL with 11 total touchdowns, will look to lead the way against a Dolphins defense that's allowed the fourth-most rushing yards in 2016.

(Photo by Sean M. Haffey/Getty Images)

14. Giants (5-3)
Last Week: 16

For the second game in a row, the Giants squeaked out a win despite some shaky play in the closing minutes. The pair of victories, though, has them in spot to battle for a playoff position, and solid play against the Bengals on Monday Night Football would give them a 6-3 record.

(Photo by Al Bello/Getty Images)

12. Bills (4-5)
Last Week: 13

Buffalo continues to compete with tough competition, but fell just short on the final play in Week 9 against Seattle. Their third straight loss brings them down to 4-4 entering their bye.

(Photo by Jonathan Ferrey/Getty Images)

11. Cardinals (3-4-1)
Last Week: 12

Despite their first-half struggles, Arizona still has a chance to challenge Seattle for the division in the second half of the season. That journey will begin this week against the 49ers, who haven't won since Week 1.

(Photo by Grant Halverson/Getty Images)

10. Vikings (5-3)
Last Week: 6

After an undefeated start, Sam Bradford's Vikings are now losers of their last three. Their remaining schedule isn't the easiest, but with strong defensive play over the last two months, the Vikings should make it out as a playoff team.

(Photo by Brace Hemmelgarn-USA TODAY Sports via Reuters)

9. Packers (4-4)
Last Week: 5

Despite pedestrian play from Aaron Rodgers, the Packers are still in the mix in the AFC North, but the Vikings' hot start and a red-hot Lions team aren't making it easy.

(Photo by Jeffrey Brown/Icon Sportswire via Getty Images)

8. Lions (5-4)
Last Week: 17

That's now four wins in their last five games after knocking off Minnesota in overtime, and all of a sudden, the Lions are looking like a tough opponent. They'll have a bye week to rest before hosting Jacksonville in Week 11.

(Photo by Brace Hemmelgarn-USA TODAY Sports via Reuters)

7. Broncos (6-3)
Last Week: 3

Denver's defense may be the best in the league, but against offensively explosive teams like Oakland, they'll face their share of struggles. They're in good position moving forward, but their offense will need a bit of figuring-out between now and the postseason.

(Photo by Ezra Shaw/Getty Images)

6. Falcons (6-3)
Last Week: 9

When they were 6-3 last season, Atlanta closed out the year with five losses over their last seven games. This time around, though, they seem to be hitting their stride.

(Photo by Don Juan Moore/Getty Images)

1. Patriots (7-1)
Last Week: 1

The class of the NFL is starting to separate itself from the pack as we enter the season's second half, but the Patriots sit comfortably above everybody else. A Super Bowl 49 rematch against the Seahawks awaits on Sunday night, but their next tough matchup doesn't pop up until Dec. 18 against Denver.

(Photo by Tom Szczerbowski/Getty Images)


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