NFL picks and predictions: Week 1

Updated

The 2016 NFL season is finally here.

After an eventful offseason, all 32 teams open their seasons this weekend.

SEE ALSO: NFL power rankings: How every team stacks up before Week 1

We picked all 16 of Week 1's matchups below. Take a gander and let us know where you disagree.


Tampa Bay Buccaneers vs. Atlanta Falcons (-3)

Sunday, 1 p.m. ET

Atlanta Falcons v Tampa Bay Buccaneers
Atlanta Falcons v Tampa Bay Buccaneers

Getty

The Atlanta Falcons are fresh off an 8-8 season, with most of the team's integral parts returning. Mohamed Sanu was added to the receiving corps to replace Roddy White, to go along with Julio Jones and Devonta Freeman as Matt Ryan's primary weapons

The Tampa Bay Buccaneers, led by second-year quarterback Jameis Winston, are a young team on the rise, and could get a potentially surprising season started off right with a road win against a division rival. It should be a close matchup, but we wouldn't be surprised if Tampa makes a strong statement to begin the year.

Pick: Buccaneers

Minnesota Vikings (-2.5) vs. Tennessee Titans

Sunday, 1 p.m. ET

Minnesota Vikings v Tennessee Titans
Minnesota Vikings v Tennessee Titans

Getty

The Vikings' season took a brutal shot before it even started, with Teddy Bridgewater going down for the year. Sam Bradford is on board to run the offense, but it's clear that Adrian Peterson will have to do the heavy lifting.

Minnesota's offense may be problematic as the season wears on, but against Tennessee in Week 1, it should suffice.

Pick: Vikings

Cleveland Browns vs. Philadelphia Eagles (-4)

Sunday, 1 p.m. ET

Cleveland Browns v Tampa Bay Buccaneers
Cleveland Browns v Tampa Bay Buccaneers

Getty

Robert Griffin III won't have to wait long to face his former NFC East opponents, with the Browns traveling to Philadelphia for Week 1. The Eagles will trot out No. 2 overall pick Carson Wentz under center, and while he'll likely endure some growing pains, Cleveland will likely be the underdog in all 16 games this season.

Pick: Eagles

Cincinnati Bengals (-2.5) vs. New York Jets

Sunday, 1 p.m. ET

New York Jets v Cincinnati Bengals
New York Jets v Cincinnati Bengals

Getty

The Bengals hope to pick up where they left off last season -- before Andy Dalton's injury left their playoff hopes for dead. They'll open the season on the road against the Jets, who hope to equal last year's success -- but will have to do so against a brutal schedule.

That schedule opens with a tough on against Cincinnati. But on their home field, the Jets could get off on the right foot if Ryan Fitzpatrick is capable of completing a few big plays to his numerous weapons.

Pick: Jets

Oakland Raiders vs. New Orleans Saints (-1)

Sunday, 1 p.m. ET

Tennessee Titans v Oakland Raiders
Tennessee Titans v Oakland Raiders

Getty

After a long -- loooooong -- rebuilding process in Oakland, it seems as if the tide is starting to turn. With Derek Carr under center, Amari Cooper out wide and Latavius Murray in the backfield, the offense has weapons. Kahlil Mack, just 25, is already one of the best defensive players in the game.

It's been 13 consecutive seasons without a playoff berth for the Raiders -- actually, it's been 13 straight years without finishing better than third in their four-team division. But this could finally be the year that changes -- and it may start with a Week 1 road win over a meddling Saints team.

Pick: Raiders

San Diego Chargers vs. Kansas City Chiefs (-6.5)

Sunday, 1 p.m. ET

Divisional Round - Kansas City Chiefs v New England Patriots
Divisional Round - Kansas City Chiefs v New England Patriots

Getty

The Chargers' best offseason acquisition, first-round pick Joey Bosa, won't be suiting up for Week 1. Jamaal Charles isn't quite ready for game action though after tearing his ACL last season, but Kansas City's defense remains stout.

It may be a bit closer than the seven points Vegas is giving San Diego, but the Chiefs should be able to handle the Chargers at home.

Pick: Chiefs

Buffalo Bills vs. Baltimore Ravens (-3)

Sunday, 1 ET

New York Giants v Buffalo Bills
New York Giants v Buffalo Bills

Getty

The Bills are looking to take advantage of a Brady-less AFC East through the first month of the season, but they'll first need to get through the Ravens in their home building. It will be Tyrod Taylor's first game against the team he began has career with as a backup, so be on the lookout for a potential #RevengeGame there.

It'll be a close one in Baltimore, but on their home field, the Ravens should be able to outlast Rex Ryan's Bills.

Pick: Ravens

Chicago Bears vs. Houston Texans (-6)

Sunday, 1 p.m. ET

Arizona Cardinals v Houston Texans
Arizona Cardinals v Houston Texans

Getty

The Bears seem to be transitioning with both Brandon Marshall and Matt Forte departing over the last two offseasons. Jay Cutler remains, though, with Alshon Jeffery and Jeremy Langford as his top offensive weapons.

The Texans are taking a risk in entrusting Brock Osweiler with their offense, but with one of the game's top receivers at his disposal in DeAndre Hopkins -- and Lamar Miller running the ball -- Houston should be able hang in with teams thanks to their top-flight defense.

Pick: Texans

Green Bay Packers (-5) vs. Jacksonville Jaguars

Sunday, 1 p.m. ET

Green Bay Packers v Buffalo Bills
Green Bay Packers v Buffalo Bills

Getty

The Jacksonville Jaguars are definitely a team on the rise. Blake Bortles has a plethora of options to get the ball to, with a two-headed attack in the backfield balancing out the offense. They could be a trendy pick to make some noise late in the season because of it.

But in Week 1? They'll have their work cut out for them. After a disappointing ending to last season, the Packers are motivated for a deep postseason run -- and don't forget that Jordy Nelson is back in the mix this year.

Pick: Packers

Miami Dolphins vs. Seattle Seahawks (-10.5)

Sunday, 4:05 p.m. ET

Seattle Seahawks v Oakland Raiders
Seattle Seahawks v Oakland Raiders

Getty

Seattle is never an easy place to play for any opponent, and Week 1 will be no different for the Dolphins. After a rocky start to last season, the Seahawks are surely determined to get off on the right foot this year. A 10.5-point spread is ambitious, but in any event, Seattle shouldn't have a problem getting the the job done.

Pick: Seahawks

New York Giants vs. Dallas Cowboys (-1)

Sunday, 4:25 p.m. ET

New York Giants v New York Jets
New York Giants v New York Jets

Getty

The Giants improved their defense via free agency over the offseason, and could have two "new" passing options in 2016 -- rookie Sterling Shephard and 29-year-old Victor Cruz, who last suited up for a regular season game in 2014.

The Cowboys are very much an unknown with rookie Dak Prescott under center for the foreseeable future. He should be good enough to get Dez Bryant the ball, while Ezekiel Elliott should take some pressure off his shoulders. But that's a lot riding on two rookies in their first-ever NFL action.

Pick: Giants

Detroit Lions vs. Indianapolis Colts (-3.5)

Sunday, 4:25 p.m. ET

Playoffs Upheaval Football
Playoffs Upheaval Football

AP

Without Calvin Johnson, the Lions will have trouble scoring. The Colts defense isn't known for providing much resistance, but a healthy -- and now paid -- Andrew Luck will look to open the season strong against a divisional opponent.

Pick: Colts

New England Patriots vs. Arizona Cardinals (-6)

Sunday, 8:30 p.m. ET

Arizona Cardinals v Houston Texans
Arizona Cardinals v Houston Texans

Getty

Many people's predicted Super Bowl 50 matchup takes the field on Sunday night, though without the most recognizable face from either side. Jimmy Garoppolo will step in for a suspended Tom Brady, going up against what may be the best all-round teams in the NFL.

On its home field, Arizona is the favorite -- as it should be. The Patriots will likely survive their Brady-less stretch mostly unscathed, but a strong club, backed by Carson Palmer, can handle them.

Pick: Cardinals

Pittsburgh Steelers (-3) vs. Washington Redskins

Monday, 7:10 p.m. ET

Pittsburgh Steelers v New Orleans Saints
Pittsburgh Steelers v New Orleans Saints

Getty

Monday night's doubleheader kicks off in Washington, as Kirk Cousins opens up his contract season by attempting to prove that last year's success wasn't a fluke. He'll have his work cut out for him against a good Steelers team -- though Pittsburgh will be without top back Le'Veon Bell for the first three weeks.

Still, the Ben Roethlisberger-to-Antonio Brown connection will likely connect on enough big-time plays to carry the Steelers in this one.

Pick: Steelers

Los Angeles Rams (-2.5) vs. San Francisco 49ers

Monday, 10:20 p.m. ET

Kansas City Chiefs v Los Angeles Rams
Kansas City Chiefs v Los Angeles Rams

Getty

Week 1 of the season rounds out on the west coast, where the Rams will play their first game as a Los Angeles franchise in more than two decades. Todd Gurley is the player to watch in this one, as the Rams are without a major playmaker under center, and the Niners ranked 29th against the run in 2015.

Pick: Rams

Follow us on Facebook, Instagram and Twitter.

Week 1 NFL Power Rankings:

Advertisement