Louisville junior quarterback Lamar Jackson announced Friday he will enter the 2018 NFL Draft.
Jackson, who won the 2016 Heisman Trophy and was a finalist for the honor in 2017, made his decision known via Twitter.
"My team in Louisville has produced some of the best memories of my life," Jackson wrote on Twitter. "I have had the pleasure of being in the presence of some of the best professors, coaches, advisers, training staff, athletes and fans, in the nation. With their help, I have been able to grow not only as a quarterback, but as a teammate, student, and most of all, a man."
The dual-threat quarterback flourished under coach Bobby Petrino and has been compared to former Atlanta Falcons first-round pick Michael Vick because of his strong arm and running skills.
"I would like to thank the University of Louisville, Coach Petrino and the coaching staff, my teammates and the fans," Jackson wrote on Twitter. "It has been nothing short of an honor to be a member of #CardsNation and to play for this university."
Jackson started since his freshman year in 2015, topped by his 2016 Heisman season when he compiled 5,114 total yards (3,543 passing, 1,571 rushing) and 51 total touchdowns (30 passing, 21 rushing).
2016 Heisman Trophy winner Lamar Jackson
2016 Heisman Trophy winner Lamar Jackson
NEW YORK CITY, NY - DECEMBER 10: 2016 Heisman Trophy finalist University of Louisville quarterback Lamar Jackson (4) answers questions during the 81st Annual Heisman Trophy press conference on December 10, 2016, at the Marriott Marquis in New York City. (Photo by Rich Graessle/Icon Sportswire via Getty Images)
NEW YORK, NY - DECEMBER 10: A detail of Lamar Jackson of the Louisville Cardinals during a press conference prior to the 2016 Heisman Trophy Presentation at the Marriott Marquis on December 10, 2016 in New York City. (Photo by Michael Reaves/Getty Images)
LOUISVILLE, KY - OCTOBER 22: Lamar Jackson #8 of the Louisville Cardinals runs drills before the game against the North Carolina State Wolfpack at Papa John's Cardinal Stadium on October 22, 2016 in Louisville, Kentucky. (Photo by Andy Lyons/Getty Images)
CHESTNUT HILL, MA - NOVEMBER 05: Lamar Jackson #8 of Louisville reacts following a game against Boston College at Alumni Stadium on November 5, 2016 in Chestnut Hill, Massachusetts. (Photo by Billie Weiss/Getty Images)
October 1, 2016: Louisvilles quarterback Lamar Jackson getting off the bus and entering Death Valley during pre-game between the Clemson Tigers and the Louisville Cardinals at Memorial Stadium in Clemson, SC. (photo by Doug Buffington/ Icon Sportswire).
CLEMSON, SC - OCTOBER 01: Lamar Jackson #8 of the Louisville Cardinals speaks with his mother after his teams defeat to the Clemson Tigers at Memorial Stadium on October 1, 2016 in Clemson, South Carolina. The Clemson Tigers defeated the Louisville Cardinals 42-36. (Photo by Grant Halverson/Getty Images)
Sep 17, 2016; Louisville, KY, USA; Louisville Cardinals quarterback Lamar Jackson (8) runs the ball against the Florida State Seminoles during the second half at Papa John's Cardinal Stadium. Louisville defeated Florida State 63-20. Mandatory Credit: Jamie Rhodes-USA TODAY Sports
Nov 5, 2016; Boston, MA, USA; Louisville Cardinals quarterback Lamar Jackson (8) prepares to make a pass during the second quarter against the Boston College Eagles at Boston College at Alumni Stadium. Mandatory Credit: Greg M. Cooper-USA TODAY Sports
LOUISVILLE, KY - SEPTEMBER 17: Lamar Jackson #8 of the Louisville Cardinals celebrates after a Louisville touchdown during the game against the Florida State Seminoles at Papa John's Cardinal Stadium on September 17, 2016 in Louisville, Kentucky. (Photo by Bobby Ellis/Getty Images)
LOUISVILLE, KY - NOVEMBER 12: Lamar Jackson #8 of the Louisville Cardinals runs with the ball during the game against the Wake Forest Deamon Deacons at Papa John's Cardinal Stadium on November 12, 2016 in Louisville, Kentucky. (Photo by Andy Lyons/Getty Images)
LOUISVILLE, KY - SEPTEMBER 17: Lamar Jackson #8 of the Louisville Cardinals celebrates with Jamari Staples #2 after he ran for a touchdown against the Florida State Seminoles at Papa John's Cardinal Stadium on September 17, 2016 in Louisville, Kentucky. (Photo by Andy Lyons/Getty Images)
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Jackson had another outstanding season in 2017 but the Cardinals finished 8-5, including a 31-27 loss to Mississippi State in the TaxSlayer Bowl on Dec. 30 when he threw four interceptions in his last college game. Jackson had just six interceptions in the regular season.
In 2017, Jackson broke his own rushing record with 1,601 yards (and 18 running TDs) while adding 3,660 passing yards and 27 touchdowns.
In his three years with the Cardinals, Jackson passed for 9,043 yards and 69 touchdowns while adding 4,132 yards and 50 scores on the ground.