The most serious charges against drug lord 'El Chapo'

Infamous drug lord "El Chapo" pleaded not guilty to over a dozen counts in a New York federal court Friday.

Joaquin Guzman Loera, who often goes by his Spanish nickname, was extradited to the U.S. earlier this week. He faces 17 charges that allege he ran Mexico's Sinaloa cartel from 1989 to 2014.

During that time, the cartel imported more than 200 metric tons of cocaine to the U.S., along with heroin, methamphetamine and marijuana. Guzman has also been charged in connection with the assassinations of thousands of competitors.

SEE MORE: Here's Video Of The Explosive Raid That Led To El Chapo's Capture

The Justice Department estimates Guzman smuggled $14 billion in narcotic sales from the U.S. and Canada back to Meixco.

If convicted, Guzman faces life in prison. Prosecutors took the death penalty off the table during negotiations because Mexico is against capital punishment.