The French couture house confirmed his departure exclusively to WWD, noting that his last collections were fall-winter 2017 men's wear and fall 2017 couture, which were paraded together at the National Library of France in Paris on Jan. 20.
Sources described the parting as mutual and amicable, the separation effective Jan. 31 following the expiration of his latest employment agreement.
Tisci's departure is sure to intensify speculation he is heading to Versace.
WWD broke the news on Jan. 19 that the Milan-based house has been chasing Tisci, who has long expressed his admiration for the work of the late Gianni Versace and cultivated a close friendship with his sister Donatella, whom he invited to pose in a Givenchy ad campaign in 2015.
In light of Tisci's departure, Givenchy will not stage a runway show on March 5 during Paris Fashion Week.
It is understood the fall-winter 2017 women's collection will be designed by the studio and sold to retailers in Givenchy's Paris showroom as usual.
The format for presenting the collection to the press has yet to be determined.
Givenchy's ateliers are also working on some of Tisci's final designs as sources told WWD that he has lined up stars to wear custom couture outfits at the Grammy Awards on Feb. 12 and the Academy Awards on Feb. 26.
Celebrities in Tisci's orbit include the likes of Meryl Streep, Beyonce (who on Wednesday revealed she and her husband Jay Z are expecting twins), Julia Roberts, Cate Blanchett, Ciara and Kanye West.
Givenchy did not provide any timelines for naming a successor and declined all comment on potential candidates.
Tisci's exit is the latest tremor as creative upheaval spreads through the top ranks of international fashion.
Over the past year, Christian Dior, Yves Saint Laurent, Valentino, Marni, Lanvin, Chloé, Jil Sander, Ermenegildo Zegna, Roberto Cavalli, Oscar de la Renta, Salvatore Ferragamo and Carven have all made changes in creative leadership.
Tisci invited friend and fellow designer, Donatella Versace to pose for a fall 2015 ad campaign.
As Givenchy draws up its list of potential candidates, it could draw on such well-known designers on the market as Hedi Slimane, Alber Elbaz, Peter Dundas, Clare Waight Keller and Peter Copping. Buzzy designers like Balmain's Olivier Rousteing could also be on its radar.
In a statement, Bernard Arnault, chairman and chief executive officer of LVMH Moet Hennessy Louis Vuitton, Givenchy's parent, lauded Tisci's accomplishments.
"The chapter Riccardo Tisci has written with the house of Givenchy over the last 12 years represents an incredible vision to sustain its continuous success, and I would like to warmly thank him for his core contribution to the house's development."
For his part, Tisci said, "I have very special affection for the House of Givenchy and its beautiful teams. I want to thank the LVMH group and Monsieur Bernard Arnault for giving me the platform to express my creativity over the years. I now wish to focus on my personal interests and passions."
A bundle of creative energy forever shod in Nike sneakers, Tisci was a daring, uncharacteristic hire for LVMH, which has a track record of casting media stars to helm its fashion brands, which also include Fendi, Céline, Kenzo, Loewe and Pucci.
Tisci was relatively unknown, and just 30, when he was recruited by then Givenchy ceo Marco Gobbetti, who is to assume the management helm of Burberry later this year.
Tisci succeeded a string of designers who, to varying degrees, encountered some bumps on the road to brand rejuvenation following the 1995 retirement of founder Hubert de Givenchy.
After a brief stint by John Galliano, who moved on to Dior, Alexander McQueen tried his hand. But his eclectic collections — space aliens one season, rockabilly the next — failed to galvanize the house. Next up was Julien Macdonald, who went back to a style rooted in French elegance and sophistication, but did not win much acclaim.
Tisci brought stability — and heat — to the storied name, immediately making inroads with the world's leading specialty stores and spawning a series of hit leather goods, kicking of with the Nightingale bag.
He took on design duties for men's wear three years later, and helped ignite the streetwear trend with his T-shirts printed with snarling Rottweilers or big stars, among his fetish motifs.
Setting a daring template informed by the energy of the club scene and tinged with sexual provocation, Tisci quickly became one of men's wear's most influential and original designers.
He had recently expressed a desire to extend Givenchy's reach as a lifestyle brand, having introduced a range of clothes for babies and children that is slated for July delivery.
According to market sources, Givenchy increased more than sixfold in size during the Tisci era, and the brand's revenues are now north of 500 million euros, or $540 million at current exchange. The number of employees has risen to more than 930 from 290 in 2005.
Philippe Fortunato, ceo of Givenchy, has been spearheading its recent expansion thrust and credited Tisci's "visionary qualities that led to a strong growth of the brand."
Fueled by Tisci's design chops, powerful communication skills and clutch of A-list celebrity friends, the brand has been tracking strong sales momentum and profitability, sources said. Once dependent on wholesale, Givenchy continues its retail rollout, with a Rome boutique slated to open this year and a London flagship in the works for early 2018.
A post shared by Kim Kardashian West (@kimkardashian) on May 27, 2014 at 7:58am PDT
Kim Kardashian chose Givenchy couture for her wedding.
The company also recently took over direct distribution of its collections in two key luxury markets: Dubai and Singapore.
Givenchy today boasts 72 freestanding stores, compared to only seven in 2005 when Tisci arrived.
Something of a fashion wunderkind, Tisci grew up poor in Taranto, Italy, and Como during the boom years for Versace, Armani and Valentino.
At 16, fresh out of art school, he landed a job designing fabrics for an Italian textile firm, at which point his destiny became clear. A year later, he was at Central Saint Martins and earning British scholarships that allowed him to finish his degree.
His first work experiences were in Italy, with Stefano Guerrero, Antonio Berardi, Coccapani and Ruffo Research, while he nurtured his signature label with a strong following in London. When Ruffo went bankrupt, he went soul-searching in India, gathered up his strength, and returned to Milan and staged a show that would all but seal his employment contract at Givenchy.
Once installed at the couture house, he brought a dark, Goth-tinged fierceness and severity, which he ultimately married to more romantic inclinations, clashing together such disparate influences as Victorian dressing and chola culture to produce runway fireworks.
Tisci would seen a natural for Versace, given his penchant for bold prints, demonstrative hardware and tough chic.
"I'm mature, and I'm different, but I was born a daring designer and I'm going to die as a daring designer. That is me," he told WWD last year.
As reported, Versace is rethinking the timing of its initial public offering as it embarks on a significant expansion plan ahead of a listing.
A giant heartfelt thank you to #givenchy, #lvmh, my incredible team, the magical atelier and everyone who made these 93 collections possible and all the other crazy adventures. Your love and support, in the day and in the night, will forever remain in my heart. #love #givenchy #forever
A post shared by Riccardo Tisci (@riccardotisci17) on Feb 2, 2017 at 7:33am PST
Asked on Jan. 19 about Tisci's potential arrival at the company, a spokesman said, "Donatella Versace the creative director of the company and at this time we do not have any plans to change that. Beyond that, of course, we do not comment on rumors."
Were Donatella Versace to welcome a designer of Tisci's stature would be in line with her past efforts to champion young talent. Versace tapped Christopher Kane in 2009 to help relaunch the Versus line and, when the two parted ways, she forged a new path for the brand, developing it into a seasonless line with a strong digital component, with the intention of working with young designers with a fresh approach. In 2013, she tapped Anthony Vaccarello as a guest designer for Versus, and then named him its creative director until he departed to join Saint Laurent.
To be sure, a leading designer such as Tisci would ramp up the brand's "cool factor," social media reach and appeal. The designer boasts 1.8 million followers on Instagram.
When Donatella Versace appeared in the Givenchy ads, Tisci told WWD: "There's no jealousy and no competition between us. It's a real, pure friendship: Somebody who's part of my gang, part of my family. We want to give a message of friendship and love."
At that time, Versace echoed the sentiment, and gave a resounding endorsement to her Paris-based counterpart: "Riccardo Tisci is extremely talented and, above all, my dear friend. We are family. I want to get rid of the old system, work together, support each other and make fashion a true global community."
The Blackstone Group bought a 20 percent stake in Versace in 2014. Family members hold the rest of the equity.
Versace's own stores are increasingly becoming the engine behind the brand's growth, as shown by its performance in 2015, when retail sales were up 28.9 percent to 400.7 million euros, or $440.7 million.
In 2015, earnings before interest, taxes, depreciation and amortization rose 19.9 percent to 81 million euros, or $89.1 million. The Milan-based group saw revenues increase 17.5 percent to 645 million euros, or $709.5 million.
Dollar figures were converted from the euro at average exchange rates for the periods in question.