Johnny Depp and Vanessa Paradis' son Jack has 'serious health problems': Report

Johnny Depp and Vanessa Paradis' son is not doing well.

The 45-year-old French actress reportedly missed the Paris premiere of her latest film, A Knife in the Heart, due to her 16-year-old son, Jack's (whose real name is John Christopher), "serious health problems."

According to the French outlet Public, the movie's director, Yann Gonzalez, shared the news with press at the event.

"Unfortunately, Vanessa Paradis was not able to join us tonight, she had to be absent because of her son's serious health problems," Gonzalez said.

ET has reached out to Depp's rep for comment.

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Johnny Depp and Vanessa Paradis together
Actor Johnny Depp (in Giorgio Armani) and wife, actress Vanessa Paradis (in Chanel Haute Couture), arrive at the 2008 Academy Awards??, held at the Kodak Theater in Hollywood. This photo appears on page 504 in Frank Trapper's RED CARPET book. (Photo by Frank Trapper/Corbis via Getty Images)
Johnny Depp and Vanessa Paradis (Photo by Tony Barson Archive/WireImage)
Johnny Depp and Vanessa Paradis during Mont Blanc 100th Anniversary Party - Arrivals at Palexpo in Geneva, Switzerland. (Photo by Tony Barson Archive/WireImage)
BEVERLY HILLS, CA - JANUARY 16: Johnny Depp and Vanessa Paradis attend The 63rd Annual GOLDEN GLOBE AWARDS - Red Carpet Arrivals at The Beverly Hilton on January 16, 2006 in Beverly Hills, CA. (Photo by Stefanie Keenan/Patrick McMullan via Getty Images)
BEVERLY HILLS, CA - JANUARY 16: (L-R) Actor Johnny Depp and wife Vanessa Paradis arrives to the 63rd Annual Golden Globe Awards at the Beverly Hilton on January 16, 2006 in Beverly Hills, California. (Photo by Frazer Harrison/Getty Images)
Johnny Depp and partner Vanessa Paradis attend his hand and footprint ceremony at world-famous Grauman's Chinese Theatre. (Photo by Frank Trapper/Corbis via Getty Images)
Johnny Depp, nominee Best Actor in a Leading Role for Finding Neverland, and Vanessa Paradis (Photo by Ron Galella/WireImage)
Johnny Depp, nominee Best Actor in a Leading Role for 'Finding Neverland,' and Vanessa Paradis (Photo by SGranitz/WireImage)
Johnny Depp and Vanessa Paradis during 11th Annual Screen Actors Guild Awards - Green Room at Shrine Auditorium in Los Angeles, California, United States. (Photo by Ron Wolfson/WireImage)
Actor Johnny Depp and his partner Vanessa Paradis arrive for the UK charity film premiere of Finding Neverland in aid of Great Ormond Street Hospital Children's Charity (GOSHCC) at the Odeon Leicester Square in central London. The film, directed by Marc Forster, tells the story of how Peter Pan author JM Barrie wrote the classic tale after befriending four fatherless boys and their mother. (Photo by Ian West - PA Images/PA Images via Getty Images)
Johnny Depp and Vanessa Paradis during 76th Annual Academy Awards - Governor's Ball at The Kodak Theater in Hollywood, California, United States. (Photo by Donato Sardella/WireImage)
BEVERLY HILLS, CA - JANUARY 25: Actor Johnny Depp (L) and Girlfriend Vanessa Paradis attend the 61st Annual Golden Globe Awards at the Beverly Hilton Hotel on January 25, 2004 in Beverly Hills, California. (Photo by Carlo Allegri/Getty Images)
Johnny Depp and wife Vanessa Paradis (Photo by Jim Spellman/WireImage)
(Original Caption) Johnny Depp and Vanessa Paradis. (Photo by Frank Trapper/Corbis via Getty Images)
ITALY - SEPTEMBER 08: 58th Venice Film Festival: US actor Johnny Depp and fiancee French singer and actress Vanessa Paradis attended the presentation of the film 'From Hell' by Albert and Allen Hugues in Venice, Italy on September 08th, 2001. (Photo by Eric VANDEVILLE/Gamma-Rapho via Getty Images)
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Depp and Paradis dated from 1998 to 2012 and share two children together, 19-year-old daughter Lily-Rose and 16-year-old son Jack.

The news comes a week after Rolling Stone published an in-depth and personal interview with the Pirates of the Caribbean star, in which he opened up about being "as low as I could have been" during the past couple of years.

"I was as low as I believe I could have gotten," Depp said, recalling his emotional state in the midst of his failed marriage to Amber Heard and his simultaneously collapsing financial situation.

"The next step was, ‘You’re going to arrive somewhere with your eyes open and you’re going to leave with your eyes closed,’" he added. "I couldn’t take the pain every day."

Additionally, earlier this month, fans questioned Depp's health after photos of him looking extremely thin were posted online. Despite concerns, a source told ET that the actor is "healthy."

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