Steve Martin, 72, and Martin Short, 68, revealed on "Jimmy Kimmel Live!" Tuesday that they have "colonoscopy parties" every other year with Tom Hanks, 61, and fellow friend Walter Parks to have some fun ahead of the procedure.
"We're very excited,'' Short said. "We go to Steve's house around 5 p.m. the night before. We call it 'Colonoscopy Eve' in Canada."
They go through the process of avoiding solid foods, consuming liquids and clearing their bowels to get ready.
"And it's catered,'' Martin said. "There's Jell-O, you know, there's not much you can (eat). You have to purge all day and then we toast."
"We thought, everybody at our age ... at a certain age, you want to get a colonoscopy," Martin said. "We all came over, we played poker and we watched some funny movie and you drink all this stuff."
Short also joked about the portion of the party that isn't so fun.
"What's shocking is with Steve, you know, he's a wealthy man,'' he said. "Who would think he would have one bathroom? I mean, by 10 p.m., the bathroom looks like Day 14 of a Carnival cruise."
"I thought the bathroom ended up looking like a Jackson Pollock," Martin added.
The four friends share one car on the ride to get their colonoscopies the next day, playing cards to determine who has to go last for his exam, the duo said.
"It was fun,'' Martin said about the party. "It's a great way to do something that you should do."
Martin Short out and about
Martin Short out and about
LOS ANGELES, CA - MAY 11: Martin Short talks to the audience at 'Neflix Is A Joke - A Celebration of Netflix Stand-Up FYC Event' at Netflix FYSEE At Raleigh Studios on May 11, 2018 in Los Angeles, California. (Photo by Michael Tullberg/Getty Images)
LOS ANGELES, CA - MAY 11: Actor / Comedian Martin Short attends the #NETFLIXFYSEE 'Neflix Is A Joke' at Netflix FYSEE At Raleigh Studios on May 11, 2018 in Los Angeles, California. (Photo by Paul Archuleta/FilmMagic)
NEW YORK - APRIL 11: The Late Show with Stephen Colbert and guest Martin Short during Wednesday's April 11, 2018 show. (Photo by Scott Kowalchyk/CBS via Getty Images)
NEW YORK, NY - APRIL 08: Martin Short attends the opening night of 'Mean Girls' on Broadway at August Wilson Theatre on April 8, 2018 in New York City. (Photo by Noam Galai/Getty Images)
SANTA MONICA, CA - MARCH 01: Martin Short speaks onstage during the Oscar Wilde Awards 2018 at Bad Robot on March 1, 2018 in Santa Monica, California. (Photo by Alberto E. Rodriguez/Getty Images for US-Ireland Alliance )
SANTA MONICA, CA - MARCH 01: Actor Martin Short arrives at the 13th Annual Oscar Wilde Awards on March 1, 2018 in Santa Monica, California. (Photo by Jerod Harris/WireImage)
NEW YORK, NY - NOVEMBER 29: Martin Short attends the 'Meteor Shower' Broadway Opening Night at the Booth Theatre on November 29, 2017 in New York City. (Photo by Dia Dipasupil/Getty Images)
WASHINGTON, DC - OCTOBER 22: Martin Short arrives to the 2017 Mark Twain Prize for American Humor at The Kennedy Center on October 22, 2017 in Washington, DC. (Photo by Paul Morigi/Getty Images)
HOLLYWOOD, CA - SEPTEMBER 26: Actor Martin Short attends the Premiere of HBO's 'Spielberg' at Paramount Studios on September 26, 2017 in Hollywood, California. (Photo by Allen Berezovsky/WireImage for Fashion Media)
HOLLYWOOD, CA - JUNE 08: Actors Steve Martin (L) and Martin Short pose backstage during American Film Institute's 45th Life Achievement Award Gala Tribute to Diane Keaton at Dolby Theatre on June 8, 2017 in Hollywood, California. 26658_001 (Photo by Alberto E. Rodriguez/Getty Images for Turner)
HOLLYWOOD, CA - JUNE 08: Actors Steve Martin (L) and Martin Short speak onstage during American Film Institute's 45th Life Achievement Award Gala Tribute to Diane Keaton at Dolby Theatre on June 8, 2017 in Hollywood, California. 26658_007 (Photo by Kevin Winter/Getty Images)
THE TONIGHT SHOW STARRING JIMMY FALLON -- Episode 0664 -- Pictured: (l-r) Comedian Martin Short arrives for an interview on April 28, 2017 -- (Photo by: Andrew Lipovsky/NBC/NBCU Photo Bank via Getty Images)
BEVERLY HILLS, CA - APRIL 25: Actor Martin Short attends the Natural Resources Defense Council's STAND UP! for the Planet benefit at Wallis Annenberg Center for the Performing Arts on April 25, 2017 in Beverly Hills, California. (Photo by Paul Archuleta/FilmMagic)
BEVERLY HILLS, CA - FEBRUARY 26: Martin Short attends the 2017 Vanity Fair Oscar Party at Wallis Annenberg Center for the Performing Arts on February 26, 2017 in Beverly Hills, California. (Photo by Taylor Hill/Getty Images)
He celebrated turning 50 this year by having former TODAY anchor Katie Couric walk him through the process and go through the results in a hilarious scene while also stressing the importance of the exam. Couric's first husband, Jay Monahan died at 42 of colon cancer in 1998.
The legendary comedians correctly noted to Kimmel on Tuesday that colon cancer screenings should start at 45 instead of 50 under new guidelines issued by the American Cancer Society last month.
Colonoscopy parties don't need to be as frequent as every other year like those of the four friends. People who are in good health with no increased risk should have a colonoscopy every 10 years, according to the American Cancer Society.
If you're at increased or high risk of colorectal cancer (or think you might be), talk to your health care provider to learn more. Your provider can suggest the best screening option for you, as well as determine what type of screening schedule you should follow, based on your individual risk.
Tom Hanks through the years
Tom Hanks through the years
WEST HOLLYWOOD, CA - 1986: Two-time Academy Award-winning actor Tom Hanks poses during a 1986 West Hollywood, California studio photo session to promote his newest movie 'The Money Pit.' Hanks went on to become one of America's favorite actors, starring in such hits as 'Big,' 'Saving Private Ryan,' and 'Forest Gump.' (Photo by George Rose/Getty Images)
SPLASH (1984) TOM HANKS, JOHN CANDY SPL 004
YOU'VE GOT MAIL (1998) MEG RYAN, TOM HANKS YGML 093
THE GREEN MILE 1999 Castle Rock film with Tom Hanks
NEW YORK - NOVEMBER 9: (US TABLOIDS OUT) Actor Tom Hanks appears on MTV's Total Request Live at the MTV Times Square Studios November 9, 2004 in New York City. (Photo by Evan Agostini/Getty Images)
BURBANK, CA - JUNE 11: Actor Tom Hanks (L) appears on 'The Tonight Show with Jay Leno' at the NBC Studios on June 11, 2004 in Burbank, California. (Photo by Kevin Winter/Getty Images)
CANNES, FRANCE - MAY 17: Actors Rita Wilson and Tom Hanks, attend 'The Da Vinci Code' World Premiere & Opening Gala at the Palais during the 59th International Cannes Film Festival May 17, 2006 in Cannes, France. (Photo by Gareth Cattermole/Getty Images)
BEVERLY HILLS, CA - JANUARY 11: Actress-Producer Rita Wilson and Actor-Producer Tom Hanks arrive at the 66th Annual Golden Globe Awards held at the Beverly Hilton Hotel on January 11, 2009 in Beverly Hills, California. (Photo by Frazer Harrison/Getty Images)
LOS ANGELES, CA - NOVEMBER 14: Actor Tom Hanks arrives at the Academy of Motion Picture Arts and Sciences' Inaugural Governors Awards held at the Grand Ballroom at Hollywood & Highland Center on November 14, 2009 in Los Angeles, California. (Photo by Kevork Djansezian/Getty Images)
LARRY CROWNE 2011 Universal Pictures film with Tom Hanks and Gugu Mbatha-Raw
HOLLYWOOD, CA - FEBRUARY 13: Actors Tom Hanks and Julia Roberts pose at the 25th Annual American Society Of Cinematographers (ASC) Awards on February 13, 2011 in Hollywood, California. (Photo by Valerie Macon/Getty Images)
US director and actor Tom Hanks poses during a photocall ahead of the premiere of his latest movie 'Larry Crowne' in Berlin on June 9, 2011. The comedy romace, starring Tom Hanks and Julia Roberts, will be released in German cinemas on June 30, 2011. AFP PHOTO / JOHN MACDOUGALL (Photo credit should read JOHN MACDOUGALL/AFP/Getty Images)
Los Angeles, USA. 24th October 2012. Tom Hanks arriving at the film premiere of "Cloud Atlas" in Los Angeles on October 24th 2012
NEW YORK, NY - OCTOBER 23: Tom Hanks performs a spoken word skit during a taping of 'Late Night With Jimmy Fallon' at Rockefeller Center on October 23, 2012 in New York City. (Photo by Theo Wargo/Getty Images)
HOLLYWOOD, CA - FEBRUARY 26: Actor Tom Hanks poses in the press room at the 84th Annual Academy Awards held at the Hollywood & Highland Center on February 26, 2012 in Hollywood, California. (Photo by Kevork Djansezian/Getty Images)
NEW YORK, NY - OCTOBER 23: Tom Hanks and Jimmy Fallon play Bruce Springsteen's 'Wrecking Ball' during a taping of 'Late Night With Jimmy Fallon' at Rockefeller Center on October 23, 2012 in New York City. (Photo by Theo Wargo/Getty Images)
HOLLYWOOD, CA - NOVEMBER 16: Actor Tom Hanks presents Honoree Steve Martin with honorary award onstage during the Academy of Motion Picture Arts and Sciences' Governors Awards at The Ray Dolby Ballroom at Hollywood & Highland Center on November 16, 2013 in Hollywood, California. (Photo by Kevin Winter/Getty Images)
CENTURY CITY, CA - JANUARY 25: Actor Tom Hanks speaks onstage at the 66th Annual Directors Guild Of America Awards held at the Hyatt Regency Century Plaza on January 25, 2014 in Century City, California. (Photo by Alberto E. Rodriguez/Getty Images for DGA)
LOS ANGELES, CA - JANUARY 18: Actors Rita Wilson and Tom Hanks attend the 20th Annual Screen Actors Guild Awards at The Shrine Auditorium on January 18, 2014 in Los Angeles, California. (Photo by Kevork Djansezian/Getty Images)
NEW YORK, NY - FEBRUARY 16: Carly Rae Jepsen and Tom Hanks are seen on February 16, 2015 in New York City. (Photo by NCP/Star Max/GC Images)
US actor Tom Hanks poses during the photocall of the film ''Inferno'' in Florence on May 11, 2015. AFP PHOTO / TIZIANA FABI (Photo credit should read TIZIANA FABI/AFP/Getty Images)