Wendy Williams announces her official return to host her show after health struggle

Wendy Williams is gearing up for her big return!

The 53-year-old talk show host announced on Tuesday that she'll be returning to host her TV show, The Wendy Williams Show, on Monday, March 19, after taking a break to focus on her health. On Feb. 21, Williams shared with viewers that her doctor ordered her to take a three-week break due to her battle with hyperthyroidism and Graves' disease. 

Williams also tweeted out her thanks to Jerry O'Connell, whom she revealed will be her first-ever guest host in the show's nine-year history.

"Hey @MrJerryOC thanks for being my guest host while I'm out getting some much needed rest," Williams tweeted. "See you all Monday, March 19th! XOX, Wendy."

“Jerry has been such a good friend to me and to the show," she also said in a statement. "We’re happy to welcome him as a guest host while I’m out getting much needed rest. Can’t wait to get back in my purple chair!”

Meanwhile, O'Connell is more than happy to temporarily fill Williams' shoes.

“I am so excited to help out and fill in," O'Connell said in a statement. "We all know nobody can fill the purple chair like Wendy, but I am honored to sit with her co-hosts and to bring the many fans allthe Hot Topics they love. Like Wendy tells us, I am going to Say It Like I Mean It.”

See photos of Wendy Williams:

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Wendy Williams out and about
LATE NIGHT WITH SETH MEYERS -- Episode 622 -- Pictured: Wendy Williams during an interview on December 7, 2017 -- (Photo by: Lloyd Bishop/NBC/NBCU Photo Bank via Getty Images)
NEW YORK, NY - FEBRUARY 08: TV personality Wendy Williams poses backstage at the American Heart Association's Go Red For Women Red Dress Collection 2018 presented by Macy's at Hammerstein Ballroom on February 8, 2018 in New York City. (Photo by Astrid Stawiarz/Getty Images for AHA)
NEW YORK, NY - NOVEMBER 14: Wendy Williams attends the 50th anniversary celebration of Wilhelmina with co-host Patti Hansen on November 14, 2017 in New York City. (Photo by Mireya Acierto/Getty Images for Wilhelmina Models)

Wendy Williams and her husband Kevin Hunter held The Hunter Foundation's third-annual "Dinner With the Hunters" at Bowlmore Times Square in New York City.

(Credit: The Hunter Foundation)

NEW YORK, NY - NOVEMBER 14: Wendy Williams attends the 50th anniversary celebration of Wilhelmina with co-host Patti Hansen on November 14, 2017 in New York City. (Photo by Mireya Acierto/Getty Images for Wilhelmina Models)
NEW YORK, NY - SEPTEMBER 23: TV personality Wendy Williams poses in the VIP Lounge during the 2017 Global Citizen Festival in Central Park on September 23, 2017 in New York City. (Photo by Noam Galai/Getty Images for Global Citizen)
NEW YORK, NY - SEPTEMBER 18: Wendy Williams poses for a photo on the observation deck after taking part in the ceremonial lighting of the Empire State Building to celebrate the ninth season of 'The Wendy Williams Show' on September 18, 2017 in New York City. (Photo by Cindy Ord/Getty Images)
ATLANTA, GA - AUGUST 29: TV personality Wendy Williams attends Wendy Digital Event at Atlanta Tech Village Rooftop on August 29, 2017 in Atlanta, Georgia. (Photo by Paras Griffin/Getty Images)
NEW YORK, NY - JULY 26: Wendy Williams visits at SiriusXM Studios on July 26, 2017 in New York City. (Photo by Robin Marchant/Getty Images)
NEW YORK, NY - JULY 13: American televison host Wendy Williams visits SiriusXM Studios on July 13, 2017 in New York City. (Photo by Nicholas Hunt/Getty Images)
NEW YORK, NY - JULY 11: Wendy Williams gets immortalized with her handprints on the wall of fame at Planet Hollywood during a celebration for her Hunter Foundation Charity that helps fund programs for families and youth communities in need of help and guidance at Planet Hollywood Times Square on July 11, 2017 in New York City. (Photo by Bruce Glikas/Bruce Glikas/Getty Images)
NEW YORK, NY - APRIL 17: Actress Wendy Williams leaves the 'AOL Build' taping at the AOL Studios on April 17, 2017 in New York City. (Photo by Ray Tamarra/GC Images)
NEW YORK, NY - APRIL 17: Talk show host Wendy Williams attends Build Series to discuss her daytime talk show at Build Studio on April 17, 2017 in New York City. (Photo by Steve Zak Photography/FilmMagic)
NEW YORK, NY - APRIL 12: TV personality Wendy Williams attends Resident Magazine celebration at Lovage on April 12, 2017 in New York City. (Photo by Astrid Stawiarz/Getty Images)
NEW YORK, NY - FEBRUARY 06: Television personality Wendy Williams enters the 'The Late Show With Stephen Colbert' taping at the Ed Sullivan Theater on February 06, 2017 in New York City (Photo by Ray Tamarra/GC Images)
NEW YORK, NY - APRIL 12: Television Host Wendy Williams speaks at the Vital Signs of Bowel Health Event at Apella on April 12, 2017 in New York City. (Photo by Cindy Ord/Getty Images for Allergan)
WASHINGTON, DC - NOVEMBER 21: Wendy Williams hosts the Thurgood Marshall College Fund 28th Annual Awards Gala at Washington Hilton on November 21, 2016 in Washington, DC. (Photo by Larry French/Getty Images for Thurgood Marshall College Fund)
WASHINGTON, DC - NOVEMBER 21: Television personality and host Wendy Williams attends the Thurgood Marshall College Fund 28th Annual Awards Gala at Washington Hilton on November 21, 2016 in Washington, DC. (Photo by Teresa Kroeger/Getty Images for Thurgood Marshall College Fund)
LATE NIGHT WITH SETH MEYERS -- Episode 446 -- Pictured: (l-r) Host Seth Meyers gets interviewed by Wendy Williams on November 9, 2016 -- (Photo by: Lloyd Bishop/NBC/NBCU Photo Bank via Getty Images)
NEW YORK, NY - SEPTEMBER 08: TV Personality Wendy Williams visits SiriusXM at SiriusXM Studio on September 8, 2016 in New York City. (Photo by Roy Rochlin/Getty Images)
NEW YORK, NY - OCTOBER 25: Wendy Williams attends the 33rd Annual Alzheimer's Association Rita Hayworth Gala at Cipriani 42nd Street on October 25, 2016 in New York City. (Photo by Roy Rochlin/Getty Images)
NEW YORK, NY - JULY 19: Wendy Williams visits at SiriusXM Studio on July 19, 2016 in New York City. (Photo by Rob Kim/Getty Images)
NEW YORK, NY - JUNE 9: Wendy Williams attends Pat Cleveland 'Walking with the Muses' hosted by Andre Leon Talley, Zac Posen, Anna Cleveland, Sean MacPherson, David Kuhn and Rachelle Hruska at The Jane Hotel on June 9, 2016 in New York City. (Photo by Sean Zanni/Patrick McMullan via Getty Images)
NEW YORK, NY - JUNE 09: Wendy Williams speaks on stage during the 7th Annual amfAR Inspiration Gala at Skylight at Moynihan Station on June 9, 2016 in New York City. (Photo by Kevin Tachman/Getty Images)
LATE NIGHT WITH SETH MEYERS -- Episode 373 -- Pictured: (l-r) Wendy Williams during an interview with host Seth Meyers on May 19, 2016 -- (Photo by: Lloyd Bishop/NBC/NBCU Photo Bank via Getty Images)
NEW YORK, NEW YORK - APRIL 07: (L-R) Andre Leon Talley, Wendy Williams, and Marc Jacobs attend as Marc Jacobs & Benedikt Taschen celebrate NAOMI at The Diamond Horseshoe on April 7, 2016 in New York City. (Photo by Dimitrios Kambouris/Getty Images for Marc Jacobs International, LLC)
NEW YORK, NY - APRIL 30: Wendy Williams and Chief Operating Officer at Maggy London Inc. Jonathan Lefkowitz in attendance at Maggy Loves Moms Luncheon on April 30, 2016 in New York City. (Photo by Steve Mack/Getty Images)
UNIVERSAL CITY, CA - MARCH 11: Wendy Williams visits 'Extra' at Universal Studios Hollywood on March 11, 2016 in Universal City, California. (Photo by Noel Vasquez/Getty Images)
NEW YORK, NY - FEBRUARY 10: Wendy Williams attends the Keds Centennial Celebration at Center548 on February 10, 2016 in New York City. (Photo by Santiago Felipe/Getty Images)
NEW YORK, NEW YORK - FEBRUARY 01: Talk Show host Wendy Williams attends #HealthyHeartSelfie Challenge at Initiative New York Headquarters on February 1, 2016 in New York City. (Photo by Steve Zak Photography/FilmMagic)
NEW YORK, NY - JANUARY 11: TV Personality Wendy Williams attends AOL BUILD Series at AOL Studios In New York on January 11, 2016 in New York City. (Photo by Mark Sagliocco/WireImage)
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Williams' hiatus is intended to get her medication and levels from her long-public battle with hyperthyroidism and Graves’ disease in sync. According to the Mayo Clinic, Graves' disease is "an immune system disorder that results in the overproduction of thyroid hormones." Symptoms include weight loss, anxiety, irritability, tremors in hands, bulging eyes, fatigue and heat sensitivity. 

When Williams announced her break, she noted that it feels like there are "birds swimming around my head, like a cartoon." She further quipped, "Like I'm constantly high -- but not high."

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