FOX News makes major changes to 'The O'Reilly Factor' after Bill O'Reilly's swift departure

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The show must go on!

After 21st Century Fox announced that they've officially dropped Bill O'Reilly amid scathing sexual harassment allegations, it didn't take long for FOX News to make some major changes.

O'Reilly's name was erased from his own show on Wednesday night, from "The O'Reilly Factor" to just "The Factor." Viewers instantly got a glimpse of the change during the opening graphic of the show.

Dana Perino served as a fill-in host and spent just over a minute saying goodbye to the longtime anchor who hosted the show for 20 years. Perino, who is a close friend of Megyn Kelly, began the show with a brief statement acknowledging O'Reilly's departure, but said she would address it in further detail later in the show.

At the very end of the show, the 44-year-old finally discussed O'Reilly in a prepared statement:

"Finally tonight, it is the end of an era here at the Fox News Channel. As we mentioned earlier, Bill O'Reilly is leaving this chair and this network after more than 20 years. Bill has been the undisputed king of cable news and for good reason. He is an incredibly talented broadcaster who raised the bar for interviewers everywhere. He has also held his staff to exacting standards in his quest to put the best possible program on the air and they are great. And you his audience responded in record numbers making The Factor the number one cable news show for more than 16 years. You have also been loyal and we can't tell you how much that means to everyone on 'The Factor.'"

25 PHOTOS
Bill O'Reilly through the years
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Bill O'Reilly through the years
NEW YORK, NY - OCTOBER 17: Talk Show Host Bill O'Reilly is seen on October 17, 2016 in New York City. (Photo by Patricia Schlein/Star Max/GC Images)
THE TONIGHT SHOW STARRING JIMMY FALLON -- Episode 0263 -- Pictured: (l-r) Bill O'Reilly and host Jimmy Fallon on May 14, 2015 -- (Photo by: Douglas Gorenstein/NBC/NBCU Photo Bank via Getty Images)
NEW YORK, NY - MARCH 23: Author Bill O'Reilly attends the 'Killing Jesus' World Premiere at Alice Tully Hall at Lincoln Center on March 23, 2015 in New York City. (Photo by Steve Mack/FilmMagic)
NEW YORK, NY - MARCH 23: (L-R) The cast of Nat Geo's 'Killing Jesus' Haaz Sleiman, Eoin Macken, Stephanie Leonidas, Alexis Rodney, Emmanuelle Chriqui, Joe Doyle, Chris Ryman and Kelsey Grammer pose with 'Killing Jesus' book author, Bill O'Reilly (C) at the red carpet event and world premiere of National Geographic Channel's 'Killing Jesus' at Alice Tully Hall on March 23, 2015 in New York City. (Photo by Brad Barket/Getty Images for National Geographic Channel)
NEW YORK, NY - MARCH 23: 'Killing Jesus' book author, Bill O'Reilly attends the red carpet event and world premiere of National Geographic Channel's 'Killing Jesus' at Alice Tully Hall on March 23, 2015 in New York City. (Photo by Paul Zimmerman/WireImage)
TODAY -- Pictured: Bill O'Reilly appears on NBC News' 'Today' show -- (Photo by: Peter Kramer/NBC/NBC NewsWire via Getty Images)
LATE NIGHT WITH SETH MEYERS -- Episode 0142-- Pictured: (l-r) Bill O'Reilly during an interview with host Seth Meyers on December 17, 2014 -- (Photo by: Lloyd Bishop/NBC/NBCU Photo Bank via Getty Images)
NEW YORK, NY - MAY 13: Bill O'Reilly (R) interviews Katie Couric during her visit to 'The O'Reilly Factor' at FOX Studios on May 13, 2014 in New York City. (Photo by D Dipasupil/Getty Images)
NEW YORK, NY - APRIL 09: Rob Lowe talks to host Bill O'Reilly at Fox News' 'The O'Reilly Factor' at Fox News Studios on April 9, 2014 in New York City. (Photo by Rob Kim/Getty Images)
WASHINGTON, DC - OCTOBER 28: Bill O'Reilly attends the National Geographic Channel's 'Killing Kennedy' World Premiere at The Newseum on October 28, 2013 in Washington, DC. (Photo by Kris Connor/Getty Images)
NEW YORK, NY - OCTOBER 16: TV personality Bill O'Reilly enters the 'Late Show With David Letterman' taping at the Ed Sullivan Theater on October 16, 2013 in New York City. (Photo by Ray Tamarra/WireImage)
NEW YORK, NY - MAY 14: Television host Bill O'Reilly is seen exiting'Good Morning America' studios on May 14, 2013 in New York City. (Photo by Raymond Hall/FilmMagic)
WASHINGTON, DC - FEBRUARY 27: Bill O'Reilly, host of FOX News Channel's The O'Reilly Factor, waits for the arrival of U.S. President Barack Obama during an event about Obama's 'My Brother's Keeper' initiative in the East Room at the White House February 27, 2014 in Washington, DC. As part of his 'Year of Action,' Obama announced a $200 million commitment from nine foundations to bolster the education and employment of young men and boys of color. (Photo by Chip Somodevilla/Getty Images)
THE TONIGHT SHOW STARRING JIMMY FALLON -- Episode 0170 -- Pictured: Author Bill O'Reilly on November 25, 2014 -- (Photo by: Douglas Gorenstein/NBC/NBCU Photo Bank via Getty Images)
NEW YORK, NY - JUNE 18: TV Personality Bill O'Reilly attends An Evening with Bill O'Reilly and Geraldo Rivera at 92nd Street Y on June 18, 2014 in New York City. (Photo by Mark Sagliocco/FilmMagic)
NEW YORK, NY - DECEMBER 04: Donald Trump and Bill O'Reilly attend the game between the New York Knicks and the Cleveland Cavaliers at Madison Square Garden on November 30, 2014 in New York City.NOTE TO USER: User expressly acknowledges and agrees that, by downloading and/or using this photograph, user is consenting to the terms and conditions of the Getty Images License Agreement. (Photo by Elsa/Getty Images)
NEW YORK, NY - JUNE 18: (L-R) TV Personalites Geraldo Rivera and Bill O'Reilly attend An Evening with Bill O'Reilly and Geraldo Rivera at 92nd Street Y on June 18, 2014 in New York City. (Photo by Mark Sagliocco/FilmMagic)
TODAY -- Pictured: Bill O'Reilly appears on NBC News' 'Today' show -- (Photo by: Peter Kramer/NBC/NBC NewsWire via Getty Images)
NEW YORK, NY - OCTOBER 16: Bill O'Reilly attends the 11th annual Giants of Broadcasting Honors at Gotham Hall on October 16, 2013 in New York City. (Photo by Noam Galai/WireImage)
THE VIEW - (10.1.13) Today's guest co-host is Jason Biggs ('Orange is the New Black.') Guests include Bill OReilly (author, Killing Jesus); Matt Long and Lorraine Bruce (ABC's 'Lucky 7') on ABC's 'The View.' 'The View' airs Monday-Friday (11:00 am-12:00 pm, ET) on the ABC Television Network. (Photo by Fred Lee/ABC via Getty Images) BARBARA WALTERS, BILL O'REILLY
Regis Philbin talks with Bill O'Reilly, of the O'Reilly Report, during the Court TV celebration of it's 10th anniversary at American Park inside Battery Park in New York City on July 18, 2001. photo by Gabe Palacio/ImageDirect
Bill O'Reilly attends the benefit for Homeless Children on November 16, 1989 at Letizia Restaurant in New York City. (Photo by Ron Galella, Ltd./WireImage)
THE TONIGHT SHOW WITH JAY LENO -- Episode 4420 -- Pictured: (l-r) Bill O'Reilly during an interview with host Jay Leno on March 1, 2013 -- (Photo by: Margaret Norton/NBC/NBCU Photo Bank via Getty Images)
TODAY -- Pictured: (l-r) Hoda Kotb, Kathie Lee Gifford and Bill O'Reilly appear on NBC News' 'Today' show -- (Photo by: Peter Kramer/NBC/NBC NewsWire via Getty Images)
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According to Vanity Fair, the longtime anchor found out about his own termination en route to the airport while on a week-long vacation in Italy. Bill was photographed meeting with Pope Francis before finding out the bad news.

A couple of hours after the announcement, O'Reilly released an official statement, calling the decision "disheartening."

The swift decision comes after network executives reportedly held an emergency meeting on Wednesday afternoon. The decision also divided Rupert Murdoch and his sons, Lachlan and James, who disagreed on whether or not to keep the network star. Ultimately, Rupert agreed with his sons about letting O'Reilly go.

Tucker Carlson, who joined the prime time lineup just a few months ago, will now fill O'Reilly's 8 p.m. slot.

And while the worst seems to be over for the network, one FOX News insider says that's not the case, suggesting there are more women with stories of harassment: "There's more to come."

20 PHOTOS
Stars react to Bill O'Reilly's FOX News exit
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Stars react to Bill O'Reilly's FOX News exit
Say what you will, but Bill O'Reilly always had your back. And if you were a woman, he might try for your front, too. #RipPapaBear #LSSC
Bye, Bill O'Reilly. Don't let the door grab your pussy on the way out.
I'm certainly a narcissistic actor who loves attention but I take no joy in Bill O'Reilly. He's a disgusting pig & Fox News is still garbage
Bill O'Reilly. Bill Cosby. Billy Bush. I'M THE ONLY GOOD BILLY ON TV!!!!!
Gretchen Carlson. Megyn Kelly. Greta. Roger Ailes. Bill O'Reilly....amazing amount of exits -forced and voluntary- in 1 year at Fox News.
All the threats from O'Reilly's lawyers were bluffs. @DrWendyWalsh & @LisaBloom didn't back down. O'Reilly is gone. Protest voices heard.
New book by FOX News: Killing Bill O'Reilly.
It's confirmed: O'Reilly is fired. There is no force greater than the collective power of our voice. #DropOReilly https://t.co/uz5t4bxx2M
Well Bill, I guess we wont be doing it live. 👋🏼 @oreillyfactor https://t.co/NZkCHjFCQv
I say this in all sincerity, without joy, and with malice towards one: fuck Bill O'Reilly.
3 FAMOUS OLD MEN…ROGER AILELS, BILL O’REILLY,& DONALD TRUMP HAVE SEXUALLY HARASSED WOMEN 4 YRS,TWO GOT FIRED,& ONE WAS ELECTED PRESIDENT‼️
Fox firing Bill O'Reilly is huge and hopefully sends an effective signal to all guys, however powerful, who harass & maul women
Wait, @oreillyfactor is NOT returning to @FoxNews after his vacation?! Color me SHOCKED! 😒 #HowsMyHairBill? #DidItDistractYouFromThisTweet?
ICYMI @FoxNews has been settling w/ women for YEARS they only cut @oreillyfactor loose because they were losing $$$ #ProfitsOverPeople #MAGA
I guess when you elect the head crank you don't need the junior cranks anymore. https://t.co/Y9a3Sdycb1
Bill O'Reilly Alex Jones Rudy Giuliani Tomi Lahren Chris Christie People who are having a waaaaaay different 2017 than they expected.
New book by FOX News: Killing Bill O'Reilly.
I want to thank @oreillyfactor and @jasoninthehouse for their interest in @crookedmedia, but sadly we're not hiring new hosts at this time.
Bill O'Reilly out at @FoxNews next stops: court and prison!
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