Tom Holland plays the webslinging superhero and Robert Downey Jr. is also set to reprise his role of Tony Stark.
Jon Watts is directing Sony's reboot of the "Spider-Man franchise." Marisa Tomei is set to play Aunt May and Zendaya is also on board in a mystery role. Details on Barbieri's role have not been disclosed other than being a friend to Holland's Peter Parker character.
Kevin Feige is producing with Amy Pascal.
See photos of Donald Glover:
Donald Glover joins 'Spider-Man: Homecoming'
LOS ANGELES, CA - FEBRUARY 24: Actor Donald Glover attends Vanity Fair and Barneys New York Private Dinner Celebrating 'Spotlight' Director Tom McCarthy at Chateau Marmont on February 24, 2016 in Los Angeles, California. (Photo by Jonathan Leibson/Getty Images for Vanity Fair)
PASADENA, CA - JANUARY 18: The cast of FX's 'Atlanta' (L to R) LaKeith Stanfield, Isiah Whitlock Jr., Paul Simms, Donald Glover, and Hiro Murai pose in the Getty Images Portrait Studio at the 2016 Winter Television Critics Association press tour at the Langham Hotel on January 18, 2016 in Pasadena, California. (Photo by Maarten de Boer/Getty Images Portrait)
PASADENA, CA - JANUARY 16: Creator/Executive Producer/Writer/Actor Donald Glover speaks onstage during the 'Atlanta' panel discussion at the FX portion of the 2015 Winter TCA Tour at the Langham Huntington Hotel on January 16, 2016 in Pasadena, California. (Photo by Frederick M. Brown/Getty Images)
PASADENA, CA - JANUARY 15: Actor Donald Glover attends the FOX winter TCA 2016 All-Star party at The Langham Huntington Hotel and Spa on January 15, 2016 in Pasadena, California. (Photo by Jason LaVeris/FilmMagic)
BEVERLY HILLS, CA - JANUARY 10: Actor Donald Glover attends InStyle and Warner Bros. 73rd Annual Golden Globe Awards Post-Party at The Beverly Hilton Hotel on January 10, 2016 in Beverly Hills, California. (Photo by Lester Cohen/WireImage)
Actor/rapper Donald Glover attends the GQ Men of The Year Party - 20th Anniversary, in West Hollywood, California, on December 3, 2015. AFP PHOTO/VALERIE MACON / AFP / VALERIE MACON (Photo credit should read VALERIE MACON/AFP/Getty Images)
WESTWOOD, CA - NOVEMBER 19: Donald Glover aka Childish Gambino and Composer Ludwig Goransson attends the premiere Of Warner Bros. Pictures' 'Creed' at Regency Village Theatre on November 19, 2015 in Westwood, California. (Photo by Todd Williamson/Getty Images)
NEW YORK, NY - NOVEMBER 02: Donald Glover attends the 12th annual CFDA/Vogue Fashion Fund Awards at Spring Studios on November 2, 2015 in New York City. (Photo by Nicholas Hunt/Getty Images)
TORONTO, ON - SEPTEMBER 13: Actor Donald Glover at the Vanity Fair toast of 'Freeheld' at TIFF 2015 presented by Hugo Boss and supported by Jaeger-LeCoultre at Montecito Restaurant on September 13, 2015 in Toronto, Canada. (Photo by George Pimentel/Getty Images for Vanity Fair)
TORONTO, ON - SEPTEMBER 11: Actor Donald Glover attends the premiere for 'The Martian' at Roy Thomson Hall during the 2015 Toronto International Film Festival on September 11, 2015 in Toronto, Canada. (Photo by Taylor Hill/FilmMagic)
HOLLYWOOD, CA - JUNE 25: Actor Donald Glover arrives at the Los Angeles World Premiere of Warner Bros. Pictures 'Magic Mike XXL' at TCL Chinese Theatre on June 25, 2015 in Hollywood, California. (Photo by Barry King/Getty Images)
MANCHESTER, TN - JUNE 13: Donald Glover aka Childish Gambino performs on June 13, 2015 in Manchester, Tennessee. (Photo by Erika Goldring/WireImage)
NEW YORK - FEBRUARY 24: Donald Glover seen out in Tribeca on FEBRUARY 24, 2015 in New York, New York. (Photo by Josiah Kamau/BuzzFoto via Getty Images)
NEW YORK, NY - FEBRUARY 24: Actor Donald Glover visits the SiriusXM Studios on February 24, 2015 in New York City. (Photo by Ilya S. Savenok/Getty Images)
LOS ANGELES, CA - FEBRUARY 08: Actor Donald Glover attends The 57th Annual GRAMMY Awards at the STAPLES Center on February 8, 2015 in Los Angeles, California. (Photo by Jeff Vespa/WireImage)
NEW YORK, NY - OCTOBER 30: Rapper Donald 'Childish Gambino' Glover attends Power 105.1's Powerhouse 2014 at Barclays Center on October 30, 2014 in New York City. (Photo by Mike Pont/FilmMagic)
LOS ANGELES, CA - FEBRUARY 05: Childish Gambino, aka Donald Glover attends Rolling Stone and Google Play event during Grammy Week at the El Rey Theatre on February 5, 2015 in Los Angeles, California. (Photo by C Flanigan/FilmMagic)
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Plot details are still being heavily guarded as is a description of Glover's character.
Production is expected to star this summer with the film set to bow on July 7, 2017.
Glover was most recently seen in the Oscar nominated film "The Martian" opposite Matt Damon and Jessica Chastain. He can be seen next in his FX comedy "Atlanta" which premieres later this summer. Other past credits include "Lazarus" and Magic Mike XXL."
He is repped by WME, MGMT Entertainment and Ginsburg Daniels. The news was first reported by Deadline Hollywood.