The estranged couple, who wed on July 4, 1982, share three children together: Aimee, 32, Kelly, 31, and Jack, 30.
Sharon first met Ozzy in the 1970s when his band, Black Sabbath, was rising to fame and later became his manager.
Photos of Sharon and Ozzy Osbourne in happier times:
Sharon and Ozzy Osbourne
Sharon and Ozzy Osbourne are ending their 33-year marriage
GLASGOW, SCOTLAND - NOVEMBER 09: (EDITORS NOTE: Image has been converted to black and white) An alternative view of Ozzy Osbourne and Sharon Osbourne during the MTV EMA's at The Hydro on November 9, 2014 in Glasgow, Scotland. (Photo by Gareth Cattermole/MTV 2014/Getty Images for MTV)
Ozzy Osbourne and Sharon Osbourne (Photo by Ron Galella/WireImage)
UNITED STATES - MARCH 01: Ozzy Osbourne, Sharon Osbourne (Photo by The LIFE Picture Collection/Getty Images)
English rock singer Ozzy Osbourne and his wife Sharon, USA, 1987. (Photo by Dave Hogan/Hulton Archive/Getty Images)
Rock singer Ozzy Osbourne at home with his family, early 1990's. From left to right, Kelly Osbourne, Ozzy Osbourne, Jack Osbourne, Sharon Osbourne and Amme Osbourne. (Photo by Dave Hogan/Getty Images)
LOS ANGELES, CA - FEBRUARY 23: (L-R) Sharon Osbourne, Kelly Osbourne, Ozzy Osbourne, Aimee Osbourne and Jack Osbourne attend 42nd Annual Grammy Awards on February 23, 2000 at the Staples Center in Los Angeles, California. (Photo by Ron Galella, Ltd./WireImage)
009463.CA.0605.ozzy.2.AS In the backyard of their Beverly Hills home singer Ozzy Osbourne and wife Sharon Osbourne for an upfront sunday calendar story, a profile of heavyÂmetal demigod ozzy osbourne and his wife and manager sharon osbourne, who are the first couple of hard rock. this story will look at their marriage and life as citizens of beverly hills. (Photo by Al Seib/Los Angeles Times via Getty Images)
381053 04: Singer Ozzy Osbourne and wife Sharon Arden kiss at the premiere of New Line's 'Little Nicky' November 2, 2000 at Mann's Chinese Theatre in Hollywood, CA. (Photo by Chris Weeks/Liaison)
Sharon Osbourne & Ozzy Osbourne during Hollywood Premiere of 'Little Nicky' at Mann Chinese Theatre in Hollywood, California, United States. (Photo by SGranitz/WireImage)
403762 08: Musician Ozzy Osbourne pose with his wife Sharon, daughter Kelly and son Jack during the ceremony honoring him with a star on the Hollywood Walk of Fame April 12, 2002 in Hollywood, CA. (Photo by Vince Bucci/Getty Images)
The Osbournes: Kelly Osbourne, Ozzy Osbourne, Sharon Osbourne and Jack Osbourne (Photo by KMazur/WireImage)
Ozzy, Sharon and Kelly Osbourne at 'The Tonight Show with Jay Leno' at the NBC Studios in Burbank, Ca. Wednesday, Nov. 20, 2002. Photo by Kevin Winter/ImageDirect
The Osbourne family: from left, rocker Ozzy Osbourne, son Jack Osbourne, daughter Kelly Osbourne and wife Sharon Osbourne. (Photo by Steve Grayson/WireImage)
Ozzy, Kelly, Sharon and Jack Osbourne during 'School of Rock' Premiere - Arrivals at Cinerama Dome in Hollywood, California, United States. (Photo by Jean-Paul Aussenard/WireImage)
Sharon Osbourne and Ozzy Osbourne, hosts during 2005 MTV Australia Video Music Awards - Show at Big Top, Luna Park in Sydney, New South Wales, Australia. (Photo by M. Caulfield/WireImage)
SYDNEY, NSW - MARCH 3: Ozzy Osbourne and Sharon Osbourne on stage at the inaugural MTV Australia Video Music Awards at Luna Park on March 3, 2005 in Sydney, Australia. (Photo by Patrick Riviere/Getty Images)
LOS ANGELES, CA - JANUARY 17: Best Buy capitalizes on ''Bieber Fever'' and ''The Osbournes'' star power for their inaugural Big Game commercial, which features Ozzy Osbourne, Justin Bieber and Sharon Osbourne on January 17, 2011 in Los Angeles, California. (Photo by Christopher Polk/Getty Images for Best Buy)
HOLLYWOOD, CA - AUGUST 01: (L-R) TV Personality Jack Osbourne and Lisa Osbourne and TV Personalities Sharon Osbourne and Ozzy Osbourne arrive at the premiere of Columbia Pictures' 'Total Recall' held at Grauman's Chinese Theatre on August 1, 2012 in Hollywood, California. (Photo by Kevin Winter/Getty Images)
NEW YORK, NY - DECEMBER 11: Ozzy Osbourne and Sharon Osbourne visit the SiriusXM Studios on December 11, 2014 in New York City. (Photo by Ilya S. Savenok/Getty Images)
THE TONIGHT SHOW WITH JAY LENO -- Episode 2894 -- Pictured: (l-r) Couple Sharon & Ozzy Osbourne during an interview with host Jay Leno on March 11, 2005 -- (Photo by: Paul Drinkwater/NBC/NBCU Photo Bank via Getty Images)
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In 2013, Sharon emphatically denied divorce rumors during a taping of The Talk, but confirmed Ozzy's sobriety struggles at the time.
"He's been using alcohol and prescription drugs for the past year and a half. That's true. That's very true. Everybody knows he's been struggling with this his entire life," she said. "I never knew he was using prescription drugs. I knew he was drinking occasionally, but I didn't realize to the extent."
Sharon's comments came days after Ozzy made a Facebook post apologizing to his family and friends for his "insane behavior" during that period and giving a positive update on his sobriety.
"I'm happy to say that I am now 44 days sober," he wrote at the time.
However, a source tells E! News that Ozzy's sobriety is not the reason for the split and he has remained sober since 2013.