Patty Duke, Oscar-Winning actress, dies at 69

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Oscar and Emmy-winning actress Patty Duke has died at the age of 69, TheWrap has learned.

The cause of death was sepsis from a ruptured intestine.

"She was a wife, a mother, a grandmother, a friend, a mental health advocate and a cultural icon. She will be greatly missed," said her manager in a statement.

Duke started her career as a child actress on daytime soap opera "The Brighter Day," and she won an Oscar for Best Supporting Actress for "The Miracle Worker" when she was just 16, becoming the youngest Oscar winner at the time.

Patty Duke through the years:

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Patty Duke through the years
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Patty Duke, Oscar-Winning actress, dies at 69
UNITED STATES - NOVEMBER 12: JOURNEY TO THE UNKNOWN - 'Last Visitor' 6/16/69 Patty Duke (Photo by ABC Photo Archives/ABC via Getty Images)
UNITED STATES - NOVEMBER 12: JOURNEY TO THE UNKNOWN - 'Last Visitor' 6/16/69 Patty Duke (Photo by ABC Photo Archives/ABC via Getty Images)
LOS ANGELES, CA - FEBRUARY 2: Patty Duke attends 27th Annual Golden Globe Awards on February 2, 1970 at the Ambassador Hotel in Los Angeles, California. (Photo by Ron Galella, Ltd./WireImage)
LOS ANGELES, CA - FEBRUARY 2: Patty Duke attends 27th Annual Golden Globe Awards on February 2, 1970 at the Ambassador Hotel in Los Angeles, California. (Photo by Ron Galella, Ltd./WireImage)
Patty Duke during 27th Annual Golden Globe Awards at Ambassador Hotel in Los Angeles, California, United States. (Photo by Ron Galella/WireImage)
CANADA - JULY 25: Patty Duke's childhood of sorrows. 'Perfect teen' image hid tale of exploitation and abouse/H1 (Photo by Andrew Stawicki/Toronto Star via Getty Images)
John Astin and Patty Duke during 'Hedda Gabler' Los Angeles Premiere at Huntington Hartford Theater in Hollywood, California, United States. (Photo by Ron Galella/WireImage)
MARCUS WELBY, M.D. - 'Unindicted Wife' - Aired on February 25, 1975. (Photo by ABC Photo Archives/ABC via Getty Images) JOHN ASTIN;PATTY DUKE
Award-winning actress Patty Duke poses for photographers with her granddaughters, 2-year-old Elizabeth Astin (L) and 7-year-old Alexandra Astin following an unveiling ceremony, honoring Duke with the 2,260th star on the Hollywood Walk of Fame in Los Angeles, California August, 17, 2004. Duke won the Oscar for best supporting actress for "The Miracle Worker" at 16, the youngest at the time to be so named. REUTERS/Jim Ruymen JR/GN
HOLLYWOOD - AUGUST 17: Actor David Ogden Stiers kisses actress Patty Duke at the ceremony honoring Duke with a star on the Hollywood Walk of Fame August 17, 2004 in Hollywood, California. (Photo by Vince Bucci/Getty Images)
Award-winning actress Patty Duke (C) poses with sons, MacKenzie (L) and Sean Astin following an unveiling ceremony honoring Duke with the 2,260th star on the Hollywood Walk of Fame in Los Angeles, California August, 17, 2004. Duke won the Oscar for best supporting actress for "The Miracle Worker," at 16, the youngest at the time to be so named. REUTERS/Jim Ruymen JR
Patty Duke during Patty Duke Honored with a Star on the Hollywood Walk of Fame for Her Achievements in Film at 7000 Hollywood Blvd. in Hollywood, California, United States. (Photo by Jesse Grant/WireImage)
HOLLYWOOD, CA - MARCH 7: Actress Patty Duke Astin receives her award for Favorite Dual-Role on stage at the 2nd Annual TV Land Awards held on March 7, 2004 at The Hollywood Palladium, in Hollywood, California. (Photo by Kevin Winter/Getty Images)
Actress Patty Duke talks about working on a student production of 'The Four Children of Tander Welch,' in Columbia, South Carolina, on November 20, 2006. (Photo by Gerry Melendez/The State/MCT via Getty Images)
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Also Read: Joe Wambaugh, Patty Duke -- and the End of NBC's 'Features' Game

In 1963 she was given her own TV show, "The Patty Duke Show," which was created for her. She played identical cousins, the fun-loving Patty and the prim and proper Cathy. The show ran for three seasons.

Duke then transitioned to adult roles by starring in "Valley of the Dolls," which has become a cult classic. In 1970 she returned to television with "My Sweet Charlie," which won her her first Emmy award. Her second win came in 1977 with miniseries "Captains and the Kings." Her third win was for the 1980 remake of "The Miracle Worker," with Duke in the role of Anne Sullivan rather than Helen Keller.

Duke continued acting steadily into the 2000s, and has appeared on shows such as "Hawaii Five-O" and "Glee."

Also Read: Hollywood's Notable Deaths of 2016 (Photos)

The actress revealed in her autobiography that she was diagnosed with bipolar disorder in 1982, and has been an advocate for mental health.

More notable people lost in 2016:

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Notable people we lost in 2016
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Patty Duke, Oscar-Winning actress, dies at 69

January 4 -- Robert Stigwood, manager of the Bee Gees and Cream.

(Photo by Michael Putland/Getty Images)

January 4 -- Country singer Craig Strickland was found dead at age 29 from hypothermia.

(Photo via Instagram)

January 6 -- Pat Harrington, Jr., actor in 'One Day at a Time,' died at 86 from complications from Alzheimer's disease.

(Photo by CBS via Getty Images)

January 14 -- Actor Alan Rickman, popular for playing Professor Snape in the 'Harry Potter' films, died at 69 after battling cancer.

(Photo by Mike Pont/WireImage)

January 18 -- Glenn Frey, founding member of The Eagles, died at age 67 due to complications from multiple ailments.

(Photo by Tommaso Boddi/WireImage)

February 2 -- Jibri Bryan, #34, of the Mercer Bears was killed in a shooting at age 23.

(Photo by Streeter Lecka/Getty Images)

February 4 -- Maurice White, founder of Earth, Wind & Fire, died from the effects of Parkinson's disease at age 74.

(Photo by Richard E. Aaron/Redferns)

February 4 -- Astronaut Edgar D. Mitchell, the sixth person to walk on the moon, passed away at 85 under hospice care.

(Photo via NASA)

March 9 -- Beatles producer Sir George Martin passed away at age 90, as announced by Ringo Starr on Twitter.

(Photo by Vince Bucci/Getty Images)

March 16 -- Singer Frank Sinatra Jr.

(Photo by Express/Express/Getty Images)

March 29 -- Oscar winning actress Patty Duke, at the age of 69.

(Photo by ABC Photo Archives/ABC via Getty Images) 
Actor Tommy Ford passed on October 12, he was 52 years old. (Photo by Moses Robinson/Getty Images)

Agnes Nixon the creator of 'All my children' left us on September 28th at the age of 93.

(Photo by ABC Photo Archives/ABC via Getty Images)

Darrell Ward the star of 'Ice Road Truckers' life was taken in a plane crash, he was 52 years old. 
Popular voice actor Jack Riley passed on August 19th. (Photo by Michael Buckner/Getty Images)
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Duke was also relatively active on social media, her last tweet regarding her 30th wedding anniversary with her husband Mike Pearce.

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