Middle Tennessee just pulled off the biggest upset in NCAA Tournament history over Michigan State, and everyone's brackets are busted

Bracket Hack: (15) Middle Tennessee State
Bracket Hack: (15) Middle Tennessee State

Middle Tennessee State University just pulled off the biggest upset of the 2016 NCAA Tournament, and perhaps of all time.

In a 2-15 matchup with Michigan State, Middle Tennessee shocked the world, winning 90-81.

In doing so, the team became just the eighth No. 15 seed to beat a No. 2 seed in tournament history, overcoming a -16.5 spread that favored MSU.

SEE ALSO: The 25 highest-paid coaches in NCAA basketball

The massive upset likely ruined a lot of brackets. According to ESPN, MSU, who many thought should be a No. 1 seed, was selected to make the round of 32 by 91% of ESPN bracket users, the Sweet 16 by 80.9% of users, and the Final Four by 38.6% of users and win the entire tournament by 22% of users.

Middle Tennessee took the sports world by surprise right out of the gate, surging to a 15-2 lead, from which they never looked back. They were led by an even performance from their starters, getting 21 points from forward Robert Upshaw, with double-digit scoring from their other four starters.

For MTSU, it's a pretty historic moment:

Yet they handled their business casually.

They're onto the next round, where they'll meet Syracuse.

Follow AOL Sports on Facebook, Instagram and Twitter.

See photos from the thriller

NOW WATCH: New book says the NCAA treats athletes like 'indentured servants'