Affleck will join his Batman v Superman: Dawn of Justice co-stars and director Zack Snyder at Comic-Con, the annual fan convention in San Diego, where the cast of the hotly-anticipated comic clash was introduced last year.
Photos: Ben and Jen throughout the years
Ben and Jen through the years
Ben Affleck sets first public appearance after Jennifer Garner split
Actor Ben Affleck and wife, actress Jennifer Garner smile at catcher Doug Mirabelli #28 of the Boston Red Sox as they attend the game against the New York Yankees during the game at Fenway Park on October 1, 2005 in Boston, Massachusetts. (Photo by Jim McIsaac/Getty Images)
Actors and husband and wife, Ben Affleck and Jennifer Garner listen to the national anthem before the Boston Red Sox host the New York Yankees on June 2, 2007 at Fenway Park in Boston, Massachusetts. (Photo by Elsa/Getty Images)
Actress Jennifer Garner (L) and actor/director Ben Affleck, winner of Best Picture for 'Argo', departs the Oscars at Hollywood & Highland Center on February 24, 2013 in Hollywood, California. (Photo by Frazer Harrison/Getty Images)
Jennifer Garner and Ben Affleck attend the Boston Celtics versus the Orlando Magic in Game Seven of the Eastern Conference Semifinals during the 2009 NBA Playoffs at TD Banknorth Garden on May 17, 2009 in Boston, Massachusetts. (Photo by Elsa/Getty Images)
Actor Ben Affleck and actress Jennifer Garner pose during the 16th annual Critics' Choice Movie Awards at the Hollywood Palladium on January 14, 2011 in Los Angeles, California. (Photo by Christopher Polk/Getty Images for VH1)
Actress Jennifer Garner and actor-director Ben Affleck arrive at the Oscars at Hollywood & Highland Center on February 24, 2013 in Hollywood, California. (Photo by Jason Merritt/Getty Images)
Ben Affleck and Jennifer Garner are seen in Brentwood on April 24, 2015 in Los Angeles, California. (Photo by GONZALO/Bauer-Griffin/GC Images)
LOS ANGELES - FEBRUARY 9: Cast members (L to R) Colin Farrell, Michael Clarke Duncan, Jennifer Garner and Ben Affleck pose for photos at the premiere of 'Daredevil' at the Village Theatre on February 9, 2003 in Los Angeles, California. (Photo by Kevin Winter/Getty Images)
(EXCLUSIVE, Premium Rates Apply) Jennifer Garner (on screen) and Ben Affleck *Exclusive* (Photo by Mathew Imaging/FilmMagic)
(EXCLUSIVE, Premium Rates Apply) Jennifer Garner and Ben Affleck *Exclusive Coverage* (Photo by Mathew Imaging/FilmMagic)
Jennifer Garner and Ben Affleck during Ben Affleck and Jennifer Garner on Location for ''Gone Baby Gone'' in Boston, Mass - May 24, 2006 at on location in South Boston, Massachusetts, United States. (Photo by Marc Andrew Deley/FilmMagic)
Actor Ben Affleck and actress Jennifer Garner come off stage at the 24th Annual American Cinematheque Award presentation to Matt Damon at The Beverly Hilton hotel on March 27, 2010 in Beverly Hills, California.
LOS ANGELES, CA - DECEMBER 16: Jennifer Garner and Ben Affleck in Brentwood on December 16, 2012 in Los Angeles, California. (Photo by Bauer-Griffin/GC Images)
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Affleck will make his debut as the Dark Knight in the film, out next March. The actor was joined by Snyder, Superman Henry Cavill, and Wonder Woman Gal Gadot at last year's Comic-Con, where fans were shown the first footage from the film. This year, co-stars Amy Adams, Jesse Eisenberg, Jeremy Irons and Holly Hunter will also be joining the panel, which will take place Saturday morning at 10:30 a.m. in the convention's hallowed Hall H.
The Comic-Con announcement comes just one day after Affleck and Garner revealed that they were splitting up.
"After much thought and careful consideration, we have made the difficult decision to divorce," the couple said in their statement to ET. "We go forward with love and friendship for one another and a commitment to co-parenting our children whose privacy we ask to be respected during this difficult time. This will be our only comment on this private, family matter. Thank you for understanding."