NFL picks and predictions: Week 1

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The 2016 NFL season is finally here.

After an eventful offseason, all 32 teams open their seasons this weekend.

SEE ALSO: NFL power rankings: How every team stacks up before Week 1

We picked all 16 of Week 1's matchups below. Take a gander and let us know where you disagree.


Tampa Bay Buccaneers vs. Atlanta Falcons (-3)

Sunday, 1 p.m. ET

Atlanta Falcons v Tampa Bay BuccaneersGetty

The Atlanta Falcons are fresh off an 8-8 season, with most of the team's integral parts returning. Mohamed Sanu was added to the receiving corps to replace Roddy White, to go along with Julio Jones and Devonta Freeman as Matt Ryan's primary weapons

The Tampa Bay Buccaneers, led by second-year quarterback Jameis Winston, are a young team on the rise, and could get a potentially surprising season started off right with a road win against a division rival. It should be a close matchup, but we wouldn't be surprised if Tampa makes a strong statement to begin the year.

Pick: Buccaneers

Minnesota Vikings (-2.5) vs. Tennessee Titans

Sunday, 1 p.m. ET

Minnesota Vikings v Tennessee TitansGetty

The Vikings' season took a brutal shot before it even started, with Teddy Bridgewater going down for the year. Sam Bradford is on board to run the offense, but it's clear that Adrian Peterson will have to do the heavy lifting.

Minnesota's offense may be problematic as the season wears on, but against Tennessee in Week 1, it should suffice.

Pick: Vikings

Cleveland Browns vs. Philadelphia Eagles (-4)

Sunday, 1 p.m. ET

Cleveland Browns v Tampa Bay BuccaneersGetty

Robert Griffin III won't have to wait long to face his former NFC East opponents, with the Browns traveling to Philadelphia for Week 1. The Eagles will trot out No. 2 overall pick Carson Wentz under center, and while he'll likely endure some growing pains, Cleveland will likely be the underdog in all 16 games this season.

Pick: Eagles

Cincinnati Bengals (-2.5) vs. New York Jets

Sunday, 1 p.m. ET

New York Jets v Cincinnati BengalsGetty

The Bengals hope to pick up where they left off last season -- before Andy Dalton's injury left their playoff hopes for dead. They'll open the season on the road against the Jets, who hope to equal last year's success -- but will have to do so against a brutal schedule.

That schedule opens with a tough on against Cincinnati. But on their home field, the Jets could get off on the right foot if Ryan Fitzpatrick is capable of completing a few big plays to his numerous weapons.

Pick: Jets

Oakland Raiders vs. New Orleans Saints (-1)

Sunday, 1 p.m. ET

Tennessee Titans v Oakland RaidersGetty

After a long -- loooooong -- rebuilding process in Oakland, it seems as if the tide is starting to turn. With Derek Carr under center, Amari Cooper out wide and Latavius Murray in the backfield, the offense has weapons. Kahlil Mack, just 25, is already one of the best defensive players in the game.

It's been 13 consecutive seasons without a playoff berth for the Raiders -- actually, it's been 13 straight years without finishing better than third in their four-team division. But this could finally be the year that changes -- and it may start with a Week 1 road win over a meddling Saints team.

Pick: Raiders

San Diego Chargers vs. Kansas City Chiefs (-6.5)

Sunday, 1 p.m. ET

Divisional Round - Kansas City Chiefs v New England PatriotsGetty

The Chargers' best offseason acquisition, first-round pick Joey Bosa, won't be suiting up for Week 1. Jamaal Charles isn't quite ready for game action though after tearing his ACL last season, but Kansas City's defense remains stout.

It may be a bit closer than the seven points Vegas is giving San Diego, but the Chiefs should be able to handle the Chargers at home.

Pick: Chiefs

Buffalo Bills vs. Baltimore Ravens (-3)

Sunday, 1 ET

New York Giants v Buffalo BillsGetty

The Bills are looking to take advantage of a Brady-less AFC East through the first month of the season, but they'll first need to get through the Ravens in their home building. It will be Tyrod Taylor's first game against the team he began has career with as a backup, so be on the lookout for a potential #RevengeGame there.

It'll be a close one in Baltimore, but on their home field, the Ravens should be able to outlast Rex Ryan's Bills.

Pick: Ravens

Chicago Bears vs. Houston Texans (-6)

Sunday, 1 p.m. ET

Arizona Cardinals v Houston TexansGetty

The Bears seem to be transitioning with both Brandon Marshall and Matt Forte departing over the last two offseasons. Jay Cutler remains, though, with Alshon Jeffery and Jeremy Langford as his top offensive weapons.

The Texans are taking a risk in entrusting Brock Osweiler with their offense, but with one of the game's top receivers at his disposal in DeAndre Hopkins -- and Lamar Miller running the ball -- Houston should be able hang in with teams thanks to their top-flight defense.

Pick: Texans

Green Bay Packers (-5) vs. Jacksonville Jaguars

Sunday, 1 p.m. ET

Green Bay Packers v Buffalo BillsGetty

The Jacksonville Jaguars are definitely a team on the rise. Blake Bortles has a plethora of options to get the ball to, with a two-headed attack in the backfield balancing out the offense. They could be a trendy pick to make some noise late in the season because of it.

But in Week 1? They'll have their work cut out for them. After a disappointing ending to last season, the Packers are motivated for a deep postseason run -- and don't forget that Jordy Nelson is back in the mix this year.

Pick: Packers

Miami Dolphins vs. Seattle Seahawks (-10.5)

Sunday, 4:05 p.m. ET

Seattle Seahawks v Oakland RaidersGetty

Seattle is never an easy place to play for any opponent, and Week 1 will be no different for the Dolphins. After a rocky start to last season, the Seahawks are surely determined to get off on the right foot this year. A 10.5-point spread is ambitious, but in any event, Seattle shouldn't have a problem getting the the job done.

Pick: Seahawks

New York Giants vs. Dallas Cowboys (-1)

Sunday, 4:25 p.m. ET

New York Giants v New York JetsGetty

The Giants improved their defense via free agency over the offseason, and could have two "new" passing options in 2016 -- rookie Sterling Shephard and 29-year-old Victor Cruz, who last suited up for a regular season game in 2014.

The Cowboys are very much an unknown with rookie Dak Prescott under center for the foreseeable future. He should be good enough to get Dez Bryant the ball, while Ezekiel Elliott should take some pressure off his shoulders. But that's a lot riding on two rookies in their first-ever NFL action.

Pick: Giants

Detroit Lions vs. Indianapolis Colts (-3.5)

Sunday, 4:25 p.m. ET

Playoffs Upheaval FootballAP

Without Calvin Johnson, the Lions will have trouble scoring. The Colts defense isn't known for providing much resistance, but a healthy -- and now paid -- Andrew Luck will look to open the season strong against a divisional opponent.

Pick: Colts

New England Patriots vs. Arizona Cardinals (-6)

Sunday, 8:30 p.m. ET

Arizona Cardinals v Houston TexansGetty

Many people's predicted Super Bowl 50 matchup takes the field on Sunday night, though without the most recognizable face from either side. Jimmy Garoppolo will step in for a suspended Tom Brady, going up against what may be the best all-round teams in the NFL.

On its home field, Arizona is the favorite -- as it should be. The Patriots will likely survive their Brady-less stretch mostly unscathed, but a strong club, backed by Carson Palmer, can handle them.

Pick: Cardinals

Pittsburgh Steelers (-3) vs. Washington Redskins

Monday, 7:10 p.m. ET

Pittsburgh Steelers v New Orleans SaintsGetty

Monday night's doubleheader kicks off in Washington, as Kirk Cousins opens up his contract season by attempting to prove that last year's success wasn't a fluke. He'll have his work cut out for him against a good Steelers team -- though Pittsburgh will be without top back Le'Veon Bell for the first three weeks.

Still, the Ben Roethlisberger-to-Antonio Brown connection will likely connect on enough big-time plays to carry the Steelers in this one.

Pick: Steelers

Los Angeles Rams (-2.5) vs. San Francisco 49ers

Monday, 10:20 p.m. ET

Kansas City Chiefs v Los Angeles RamsGetty

Week 1 of the season rounds out on the west coast, where the Rams will play their first game as a Los Angeles franchise in more than two decades. Todd Gurley is the player to watch in this one, as the Rams are without a major playmaker under center, and the Niners ranked 29th against the run in 2015.

Pick: Rams

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32. Browns (0-4)

Preseason records typically mean close to nothing, but it's easy to imagine the Browns' regular season ending up about as successful as their exhibition slate.

(Photo by Don Juan Moore/Getty Images)

31. 49ers (2-2)

Chip Kelly decided on Blaine Gabbert as his starting quarterback to open the season, but it shouldn't be long before his play leads to another Colin Kaepernick takeover -- but it's unclear if the 28-year-old has much left in the tank after injury woes.

(Photo by Dustin Bradford/Getty Images)

30. Titans (3-1)

DeMarco Murray and Derrick Henry are in the offensive fold to help Marcus Mariota's attack, but with a still-futile offensive line and limited playmakers on the other side of the ball, Tennessee will probably still be in for a long season.

(AP Photo/Mark Zaleski, File)

29. Chargers (1-3)

Philip Rivers will put up his numbers, and Keenan Allen do the same, but Melvin Gordon will need to show dramatic improvement on his rookie campaign for the team's offense to build -- Joey Bosa missing the early portion of the season won't do the defense any favors, either.

(AP Photo/Lenny Ignelzi)

28. Lions (2-2)

Golden Tate -- and his fantasy owners -- will be the immediate beneficiaries of Calvin Johnson's retirement, but without him, it will be hard for Detroit to put points on the board.

(AP Photo/Gail Burton)

27. Dolphins (2-2)

2016 figures to be a make-or-break year for the Dolphins, who added Arian Foster and Mario Williams via free agency, but how Ryan Tannehill fares under center -- particularly in the Brady-less first month of the season -- will determine the team's fate.

(Jasen Vinlove-USA TODAY Sports)

26. Eagles (4-0)

After an injury-riddled preseason, it's difficult to imagine rookie Carson Wentz stepping in and leading the Eagles' offense to new heights. On the bright side, though, Philly garnered a first-rounder for Sam Bradford.

(Eric Hartline-USA TODAY Sports)

25. Saints (0-4)

Nick Fairley and Roman Harper have been added to help out a woeful defense, but Drew Brees -- with a new contract extension in hand -- doesn't have much to work with on his side of the ball.

(Chuck Cook-USA TODAY Sports)

24. Rams (2-2)

With Jared Goff faltering in the preseason, the No. 1 overall pick won't even be active for Week 1. Much will be asked of Todd Gurley in his second season, but if he can merely keep up his rookie production, LA may be able to stay afloat -- a strong defensive side of the ball will play a part as well.

(Photo by Lisa Blumenfeld/Getty Images)

23. Ravens (4-0)

Steve Smith's return from an Achiles injury in what likely will be his final NFL season will be a huge factor in the Ravens' success this season -- which isn't a great situation to be in.

(Photo by Matt Hazlett/Getty Images)

22. Bears (1-3)

After missing his rookie season, WR Kevin White is healthy and should help form a dynamic receiving duo with Alshon Jeffery. Chicago lost Matt Forte and Martellus Bennett, however -- not to mention Adam Gase, who took the Dolphins' head coaching job. Good luck, Jay Cutler.

(Photo by Nick Cammett/Diamond Images/Getty Images)

21. Buccaneers (2-2)

Second-year QB Jameis Winston looks to be in the best shape of his life, and his connection with WR Mike Evans should only strengthen as they gain experience together. Tampa Bay seems to be building an encouraging team. With a few breaks in the right direction, Tampa could surprise some people.

(AP Photo/Michael Perez)

20. Falcons (3-1)

Mohamed Sanu will theoretically produce more than Roddy White did a season ago (which isn't saying much), but the other pieces are largely the same as they were last season.

(Photo by Joel Auerbach/Getty Images)

19. Bills (1-3)

In typical Rex Ryan fashion, the Bills will likely talk a big game all season long -- especially with the Patriots vulnerable without Tom Brady until Week 5, and the Jets going up against a brutally tough schedule. But Marcell Dareus' suspension hurts. 

(Photo by Brett Carlsen/Getty Images)

18. Redskins (3-1)

Washington added Josh Norman to help its subpar defensive unit, and the team should have every chance to compete in a wide-open NFC East. Kirk Cousins, playing on a franchise tag, will have everything to prove entering free agency -- and he'll have to prove that last year's success wasn't a fluke.

(Photo by John McDonnell / The Washington Post via Getty Images)

17. Cowboys (1-3)

Tony Romo will be out until at least midseason, which leaves the offense in the hands of Dak Prescott and Mark Sanchez. Ezekiel Elliott has looked great, and is a front runner for Rookie of the Year, while any quarterback should at least be good enough to get Dez Bryant the ball. Can they hang in the NFC East until Romo returns?(Photo by Wesley Hitt/Getty Images)

16. Jaguars (1-3)

The Jags, at times, looked much better than their 5-11 record last year, and could compete for a potential playoff spot this season. With Blake Bortles able to utilize T.J. Yeldon, Denard Robinson, Allen Hurns and Allen Robinson on offense -- and with some infusion of young talent on defense -- Jacksonville should be fun to watch.

(Photo by Rich Schultz/Getty Images)

15. Raiders (1-3)

While the Raiders certainly have the pieces to finally piece together a good-to-very-good season, we're not going all-in on this bunch just yet. Though if Amari Cooper avoids a sophomore slump, Oakland should be extremely dangerous on offense -- with incredible potential on the other side of the ball, too.

(Photo by Thearon W. Henderson/Getty Images)

14. Giants (2-2)

The Giants have an opportunity to take the reigns of the NFC East thanks to Tony Romo's injured back, and New York improved its putrid 2015 defense through free agency. Odell Beckham will put up his numbers, but Victor Cruz being a suitable weapon would obviously be a welcome addition. If the Giants can form any semblance of a running game -- while performing up to par on defense -- the division should be theirs.

(Photo by Rich Barnes/Getty Images)

13. Vikings (4-0)

Teddy Bridgewater's injury is a major shot to Minnesota's Super Bowl hopes, which may have been a bit premature anyway. While the team's defense is among the league's best, Sam Bradford is being called on to lead the offense -- which is a problem.

(AP Photo/Matt Rourke)

12. Jets (1-3)

The Jets were the only 10-win team to miss the playoffs last season, and are returning a team just as talented. Ryan Fitzpatrick will need to live up to his impressive 2015 season, though, which was more productive than any of his previous 10 years. The team's defense remains stout, though, and should have them competing for a postseason berth, despite a tough schedule.

(AP Photo/Bill Kostroun, File)

11. Texans (4-0)

Adding Brock Osweiler is a major gamble, but could pay huge dividends if he can play an adequate enough quarterback to give Houston some sort of offense beyond DeAndre Hopkins' playmaking ability. J.J. Watt may miss the early portion of the season, but with so many versatile athletes on both sides of the ball, Houston should compete with the Colts for the division. 

(Photo by Wesley Hitt/Getty Images)

10. Chiefs (2-2)

The Chiefs are returning much of the same squad as last year, and are largely banking on Travis Kelce and Jeremy Maclin to carry their passing game. Jamaal Charles remains one of the best backs in the NFL, but his health -- and Andy Reid's willingness to give him the ball enough -- could get in the way of his success.

(Photo by Scott Halleran/Getty Images)

9. Colts (2-2)

Andrew Luck's injury derailed Indy's 2015 campaign, but after the front office finally decided to invest in his offensive line, a healthy year could put the Colts right back in contention to go deep into the playoffs.

(Photo by Joe Robbins/Getty Images)

8. Broncos (2-2)

After a failed Mark Sanchez experiment, the defending champion Broncos are turning to a seventh-round pick at quarterback. Trevor Siemian will start the season under center, though he's likely just keeping the seat warm for rookie Paxton Lynch. The weapons are there on offense and defense, and the Broncos won a title in 2015 with iffy quarterback play. Can they do it again?

(Photo by Helen H. Richardson/The Denver Post via Getty Images)

7. Seahawks (3-1)

Marshawn Lynch is retired, but rookie Thomas Rawls ran for 830 yards as a rookie. He and Christine Michael figure to combine for a large chunk of what Lynch produced when healthy. Russell Okung and Bruce Irvin are also both out of the picture, but the Seahawks sturdy defensive foundation remains. The pressure will likely again fall on Russell Wilson to excel with limited weaponry at his disposal -- but he's surprised us in that regard before.

(Photo by Ezra Shaw/Getty Images)

6. Steelers (1-3)

At full strength, the Steelers are among the league's best. But with Martavis Bryant out all this season while suspended, and Le'Veon Bell banned until Week 4, Pittsburgh is missing two of its three best playmakers. Still, the team should probably be headed for the postseason -- but can't seem to get out of their own way.

(Photo by Streeter Lecka/Getty Images)

5. Bengals (1-3)

The Bengals looked to finally be on their way toward a deep postseason run last year until a Andy Dalton injury derailed that thought. With much of the same core in tact, 2016 should deliver more of the same pre-Dalton-injury results.

(Photo by Rob Foldy/Getty Images)

4. Patriots (3-1)

After more than a year, the Deflategate saga came to an end when it was announced that Tom Brady would have to serve his four-game suspension this season. A quarter-season with Jimmy Garoppolo sets them a hair behind the eight-ball, but we're never ones to doubt Bill Belichick.

(Photo by Streeter Lecka/Getty Images)

3. Packers (3-1)

After a disappointing 2015 campaign relative to their standards, the Packers are looking to bounce back with a dominant year with Jordy Nelson eyeing a return from a torn ACL. Eddie Lacy was instructed to get in better shape for this season, and if his conditioning has improved, Green Bay could be in the hunt for the NFL's best record.

(Photo by Kevin C. Cox/Getty Images)

2. Panthers (2-2)

It's easy to forget, but the Panthers enjoyed their run to the Super Bowl last season without top receiver Kelvin Benjamin. They lost Josh Norman to Washington, but a strong defensive foundation -- and meaningful game experience -- should have the Panthers in contention for a deep playoff run again this season.

(Photo by Streeter Lecka/Getty Images)

1. Cardinals (1-3)

Most of last season's impact players are back for 2016, and the team added Chandler Jones, Robert Mathis and Robert Nkemdiche on the defensive end. If Carson Palmer can maintain last season's output at age 36, there's reason to believe the Cardinals can be football's best team in 2016.

(Photo by Joe Robbins/Getty Images)
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