Marijuana use may have the same temporary effects on the heart as a breakup or the death of a loved one, according to a study released Sunday.
Active marijuana users may be doubling their risk of stress cardiomyopathy, a sudden temporary weakening of the heart muscle that prevents it from pumping and can mimic a heart attack. Symptoms of the condition, also known as "broken heart syndrome," include acute chest pain, dizziness and shortness of breath.
While the muscle weakness is usually caused by acute stress or grief, at least two cases have been linked to marijuana use in medical literature, according to the study, which was presented at the annual scientific conference of the American Heart Association in New Orleans.
"There have been many reports of heart attacks, strokes and the two cases of (stress cardiomyopathy) that have been linked to marijuana," said Amitoj Singh, the lead investigator of the study.
The news comes less than a week after four states -- Maine, Massachusetts, Nevada and California -- legalized recreational marijuana use, and four others -- Montana, North Dakota, Arkansas and Florida -- legalized its medical use.
Of 33,343 people who were hospitalized with stress cardiomyopathy between 2003 and 2011, less than 1 percent -- 210 people -- were identified as marijuana users. They were generally younger males with fewer cardiovascular risk factors, which can include high cholesterol, diabetes and less high blood pressure. The group who didn't use marijuana had much higher rates of these conditions.
Still, marijuana users were twice as likely to develop stress cardiomyopathy, and had a significantly higher chance of going into cardiac arrest during stress cardiomyopathy. However, they were also more likely to have a history of depression, psychosis, anxiety disorders, alcoholism, use tobacco and abuse multiple substances.
While the link isn't strong enough to imply direct causation, researchers say it is cause for concern and further research on the effects of recreational marijuana use on cardiovascular health.
"If you are using marijuana and develop symptoms such as chest pain and shortness of breath, you should be evaluated by a healthcare provider to make sure you aren't having stress cardiomyopathy or another heart problem," Singh said in a press release.
Legal marijuana sales, dispensaries around the US, recreational and medical
Legal marijuana sales, dispensaries around the US, recreational and medical
The dispensary area at Columbia Care, one of New York City's first medicinal marijuana dispensaries, is seen, Wednesday, Jan. 6, 2016, in New York. New Yorkers with cancer, AIDS, Parkinson's disease or other qualifying conditions will be able to obtain medical marijuana as early as Thursday, 18 months after lawmakers passed what is considered one of the strictest medical cannabis programs in the nation. (AP Photo/Mary Altaffer)
In this Tuesday, Oct. 20, 2015 photo, cookbooks for use with marijuana are available inside of Salveo Health and Wellness, a licensed medical cannabis dispensary, in Canton, Ill. (AP Photo/Seth Perlman)
A sample of cannabis is shown in a sniffer at Shango Premium Cannabis, in Portland , Ore., Thursday, Oct. 1, 2015. Oregon marijuana stores have begun sales to recreational users, marking a big day for the budding pot industry in the state. Some of the more than 250 dispensaries in Oregon that already offer medical marijuana opened their doors early Thursday to begin selling the drug just moments after it became legal to do so. (AP Photo/Timothy J. Gonzalez)
NEW YORK, NY - JANUARY 07: A man leaves Columbia Care, the first medical marijuana dispensary in New York City on January 7, 2016 in New York City. The law allowing medical marijuana was signed by Governor Andrew Cuomo in 2014; the law stipulates that the legal marijuana may not be ingested by smoking it. (Photo by Andrew Burton/Getty Images)
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WASHINGTON, DC - MARCH 8: Takoma Wellness Center is a family run medical marijuana dispensary in Washington, DC. Employee, David Malpica, sets up the dispensary room before business hours on Sunday, March 8, 2015. (Sarah L. Voisin/The Washington Post via Getty Images)
Marijuana sits on a counter after being delivered to a dispensary by the courier service CannaRabbit LLC in Louisville, Colorado, U.S., on Friday, March 27, 2015. CannaRabbit and peers are rushing in as regional truckers and nationwide haulers United Parcel Service Inc. and FedEx Corp. steer clear of transporting marijuana on concerns over the lack of nationwide clearance of a practice that is still illegal in most states. Photographer: Matthew Staver/Bloomberg via Getty Images
LOS ANGELES, CA JULY 05, 2014 --- Shoppers lined up at one of many pot vendors stall at cannabis farmers market organized by California Heritage Market at West Coast Collective, a marijuana dispensary in Boyle Heights. (Photo by Irfan Khan/Los Angeles Times via Getty Images)
Vendors and growers prepare their displays for card-carrying medical marijuana patients attending Los Angeles' first-ever cannabis farmer's market at the West Coast Collective medical marijuana dispensary, on the fourth of July, or Independence Day, in Los Angeles, California on July 4, 2014 where organizer's of the 3-day event plan to showcase high quality cannabis from growers and vendors throughout the state. AFP PHOTO/Frederic J. BROWN (Photo credit should read FREDERIC J. BROWN/AFP/Getty Images)
Containers of the medical marijuana product known as 'Wax' are displayed at Los Angeles' first-ever cannabis farmer's market at the West Coast Collective medical marijuana dispensary, on the fourth of July, or Independence Day, in Los Angeles, California on July 4, 2014 where organizer's of the 3-day event plan to showcase high quality cannabis from growers and vendors throughout the state. AFP PHOTO/Frederic J. BROWN (Photo credit should read FREDERIC J. BROWN/AFP/Getty Images)
Customers wait in line early in the morning at Amazon Organics, a pot dispensary in Eugene, Ore., to purchase recreational marijuana on Thursday, Oct. 1, 2015. Oregon marijuana shops began selling marijuana Thursday for the first time to recreational users who are at least 21 years old, marking a big day for the budding pot industry. (AP Photo/Ryan Kang)
In this Oct. 20, 2015 photo, Shamay Flaharty, of Lewiston, Ill., who has multiple sclerosis and is hoping cannabis will help ease her pain and headaches, leaves with Eric Sweatt, partner and manager of Salveo Health and Wellness, a licensed medical cannabis dispensary, in Canton, Ill. Illinois will begin its first medical marijuana sales within the next two weeks. (AP Photo/Seth Perlman)
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This photo taken March 28, 2014 shows Cherry City Compassion, a medical marijuana store in Salem, Ore. Until now, medical pot shops have operated in a gray area. That's changed under a law passed last year that legalizes medical marijuana dispensaries so long as they apply for and are granted a license. (AP Photo/Chad Garland)