Mark Ruffalo responds to criticism of Matt Bomer's transgender role in 'Anything'

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Mark Ruffalo Addresses Casting Of Matt Bomer's Transgender Role

Mark Ruffalo addressed criticism regarding Matt Bomer's casting as a transgender sex worker in his new film, "Anything," saying he is "glad we are having this conversation."

Ruffalo is an executive producer on the project, in which Bomer's character befriends a suicidal man who moves from Mississippi to Los Angeles after his wife's death. The film will also star Maura Tierney, Micah Hauptman, Margot Bingham and Melora Hardin.

See photos of Mark Ruffalo through the years:

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Mark Ruffalo through the years
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Mark Ruffalo through the years
Mark Ruffalo during Chocolat Los Angeles Premiere at The Academy in Beverly Hills, California, United States. (Photo by Sam Levi/WireImage)
Mark Ruffalo & Sunrise Ruffalo during The 18th Annual IFP Independent Spirit Awards - Arrivals at Santa Monica Beach in Santa Monica, California, United States. (Photo by Jeffrey Mayer/WireImage)
NEW YORK - JUNE 27: (U.S. TABS AND HOLLYWOOD REPORTER OUT) (L-R) Actors Mark Ruffalo, Sam Rockwell, Josh Hamilton and Vanessa Ferlito attend the opening night party for the film 'On_Line' at the Coral Room June 27, 2003 in New York City. (Photo by Evan Agostini/Getty Images)
Mark Ruffalo during The 18th Annual IFP Independent Spirit Awards - Official Talent Gift Bag Produced by On 3 Productions at Santa Monica Beach in Santa Monica, California, United States. (Photo by Arun Nevader/WireImage)
Mark Ruffalo, Al Pacino, winner for Best Actor in a Miniseries, and Brittany Murphy (Photo by J. Vespa/WireImage)
LOS ANGELES - FEBRUARY 22: Actors Mark Ruffalo and Andie MacDowell present onstage during the 10th Annual Screen Actors Guild Awards at the Shrine Auditorium on February 22, 2004 in Los Angeles, California. (Photo by Kevin Winter/Getty Images)
LOS ANGELES - FEBRUARY 21: Actor Mark Ruffalo attends a rehearsal for the 10th Annual Screen Actors Guild Awards on February 21, 2004 in Los Angeles, California. (Photo by Vince Bucci/Getty Images)
SANTA MONICA, CA - FEBRUARY 28: Mark Ruffalo and Hilary Swank present an award during the 2004 IFP Independent Spirit Awards February 28, 2004 in Santa Monica, California. (Photo by Kevin Winter/Getty Images)
Sunrise Ruffalo, Mark Ruffalo and Faye Dunaway (Photo by George Pimentel/WireImage)
Mark Ruffalo during 'Collateral' Los Angeles Premiere - Red Carpet at Orpheum Theatre in Los Angeles, California, United States. (Photo by L. Cohen/WireImage)
Mark Ruffalo and Michael Mann during 'Collateral' Los Angeles Premiere - Red Carpet at The Orpheum Theatre in Los Angeles, California, United States. (Photo by Jon Kopaloff/FilmMagic)
Mark Ruffalo and his wife arrive for the premiere of the film 'Collateral' in Los Angeles. The film opens on August 6 in the United States. (Photo by Frank Trapper/Corbis via Getty Images)
Mark Ruffalo and wife Sunrise Ruffalo during 'We Don't Live Here Anymore' Los Angeles Premiere - Arrivals at The Director's Guild of America in Los Angeles, California, United States. (Photo by Jon Kopaloff/FilmMagic)
Mark Ruffalo and Francisco Costa during Calvin Klein and Vogue Magazine Host 'Rumor Has It' Los Angeles Premiere - After Party in Los Angeles, California, United States. (Photo by J. Vespa/WireImage)
Mena Suvari, Jennifer Aniston and Mark Ruffalo during Calvin Klein and Vogue Magazine Host 'Rumor Has It' Los Angeles Premiere - Red Carpet in Los Angeles, California, United States. (Photo by J. Vespa/WireImage)
Sunrise Ruffalo and Mark Ruffalo during After party for the Broadway opening night of 'Awake and Sing' at Marriott Marquis West 45th Street in New York, New York, United States. (Photo by Sylvain Gaboury/FilmMagic)
Mark Ruffalo and wife Sunrise during 'V For Vendetta' New York City Premiere - Arrivals and After Party at The Rose Theatre - Frederick P. Rose Hall in New York City, New York, United States. (Photo by Stephen Lovekin/WireImage)
CANNES, FRANCE - MAY 17: Actors Jake Gyllenhaal and Mark Ruffalo attend a photocall promoting the movie 'Zodiac' during the 60th International Cannes Film Festival on May 17, 2007 in Cannes, France. (Photo by Pascal Le Segretain/Getty Images)
Cannes, FRANCE: (From L) US actors Chloe Sevigny, Jake Gyllenhaal and Mark Ruffalo waves at the crowd as they arrive at the Festival Palace for the screening of US director David Fincher's film 'Zodiac' at the 60th edition of the Cannes Film Festival, southern France, 17 May 2007. A lavish sprinkle of Hollywood stars and veteran film-makers, a dash of arthouse fare and new international discoveries -- the Cannes filmfest celebrates its 60th edition with a tried and true recipe for success. AFP PHOTO / ANNE-CHRISTINE POUJOULAT (Photo credit should read ANNE-CHRISTINE POUJOULAT/AFP/Getty Images)
Mark Ruffalo (Photo by Tony Barson/WireImage)
PARK CITY, UT - JANUARY 25: Actor Mark Ruffalo walks in Park City on January 25, 2010 in Park City, Utah. (Photo by Ray Tamarra/Getty Images)
Mark Ruffalo Beim Photocall Zum Film 'Shutter Island' Bei Der 60. Berlinale In Berlin (Photo by Franziska Krug/Getty Images)
BEVERLY HILLS, CA - JANUARY 16: Actor Mark Ruffalo (R) and wife Sunrise Ruffalo arrive at the 68th Annual Golden Globe Awards held at The Beverly Hilton hotel on January 16, 2011 in Beverly Hills, California. (Photo by Steve Granitz/WireImage)
WEST HOLLYWOOD, CA - APRIL 27: Director/actor Mark Ruffalo, actor Orlando Bloom, and Co Chair of Maya Entertainment Jeff Valdez attend the 'Sympathy For Delicious' after party on April 27, 2011 in West Hollywood, California. (Photo by Jason Merritt/Getty Images)
Mark Ruffalo arrives at special release party for the film 'Sympathy For Delicious' held at Sky Bar, Mondrian Hotel on April 27, 2011 in West Hollywood, California. (Photo by Michael Tran/FilmMagic)
SANTA MONICA, CA - JUNE 04: Actor Mark Ruffalo arrives at Global Green USA's 15th annual Millenium Awards at the Fairmont Miramar Hotel on June 4, 2011 in Santa Monica, California. (Photo by Duffy-Marie Arnoult/Getty Images for Global Green USA)
SANTA MONICA, CA - JUNE 04: Actor Mark Ruffalo (R) and actor/director Christopher Guest attend Global Green USA's 15th annual Millenium Awards at the Fairmont Miramar Hotel on June 4, 2011 in Santa Monica, California. (Photo by Duffy-Marie Arnoult/Getty Images for Global Green)
NEW YORK CITY - MAY 7: Mark Ruffalo and wife Sunrise Coigney attend 'Schiaparelli And Prada: Impossible Conversations' Costume Institute Gala on May 7, 2012 at the Metropolitan Museum of Art in New York City. (Photo by Ron Galella, Ltd./WireImage)
WATCH WHAT HAPPENS LIVE -- Episode 677-- Pictured: (l-r) Susan Lucci, Mark Ruffalo -- (Photo by: Peter Kramer/Bravo/NBCU Photo Bank via Getty Images)
WATCH WHAT HAPPENS LIVE -- Episode 677-- Pictured: (l-r) Andy Cohen, Mark Ruffalo -- (Photo by: Peter Kramer/Bravo/NBCU Photo Bank via Getty Images)
JIMMY KIMMEL LIVE - Emmy Award-nominated 'Jimmy Kimmel Live' airs every weeknight (11:35 p.m. - 12:41 a.m., ET), packed with hilarious comedy bits and features a diverse lineup of guests including celebrities, athletes, musicians, comedians and humorous human interest subjects. The guests for THURSDAY, MAY 23 included Actor Mark Ruffalo ('Now You See Me'), Scrabble Champions Kevin Bowerman and Raymond Gao and musical guest Reggie Watts. (Photo by Randy Holmes/ABC via Getty Images) MARK RUFFALO, JIMMY KIMMEL
HOLLYWOOD, CA - MAY 23: Actor Mark Ruffalo attends a screening of Summit Entertainment's 'Now You See Me' at ArcLight Hollywood on May 23, 2013 in Hollywood, California. (Photo by David Livingston/Getty Images)
NEW YORK, NY - OCTOBER 11: Mark Ruffalo and Orlando Bloom pose backstage at 'Romeo and Juliet' on Broadway at The Richard Rogers Theater on October 11, 2013 in New York City. (Photo by Bruce Glikas/FilmMagic)
CANNES, FRANCE - MAY 19: (L-R) Mark Ruffalo, Channing Tatum, director Bennett Miller and Steve Carell attend the 'Foxcatcher' premiere during the 67th Annual Cannes Film Festival on May 19, 2014 in Cannes, France. (Photo by George Pimentel/WireImage)
CANNES, FRANCE - MAY 19: Mark Ruffalo (R) and father Frank Ruffalo attend the 'Foxcatcher' party hosted by Annapurna at Baoli Beach during the 67th Cannes Film Festival on May 19, 2014 in Cannes, France. (Photo by David M. Benett/Getty Images for Foxcatcher)
TORONTO, ON - SEPTEMBER 08: Mark Ruffalo and Steve Carell at the 'Foxcatcher' Press Conference at The Fairmont Royal York Hotel on September 8, 2014 in Toronto, Ontario. (Photo by Vera Anderson/WireImage)
TORONTO, ON - SEPTEMBER 8: Actor Mark Ruffalo with wife Sunrise pose for pictures on the red carpet for the film Foxcatcher at Roy Thompson Hall. (Vince Talotta/Toronto Star via Getty Images)
TORONTO, ON - SEPTEMBER 9: Actor Mark Ruffalo talks about Infinitely Polar Bear and Foxcatcher, his two films at TIFF from the Intercontinental hotel. Ruffalo is most known for being the Hulk in the Avengers. (Richard Lautens/Toronto Star via Getty Images)
Bella Noche Ruffalo (L) and actor Mark Ruffalo pose on arrival for the 2015 MTV Movie Awards on April 12, 2015 in Los Angeles, California. AFP PHOTO / FREDERIC J. BROWN (Photo credit should read FREDERIC J. BROWN/AFP/Getty Images)
LOS ANGELES, CA - APRIL 12: (L_R) Actorss Chris Hemsworth, Mark Ruffalo, Chris Evans and Bella Noche Ruffalo attend The 2015 MTV Movie Awards at Nokia Theatre L.A. Live on April 12, 2015 in Los Angeles, California. (Photo by Kevin Mazur/MTV1415/WireImage)
LOS ANGELES, CA - JUNE 14: Actors Zoe Saldana (L) and Mark Ruffalo attend the 'Infinitely Polar Bear' premiere during the 2015 Los Angeles Film Festival at Regal Cinemas L.A. Live on June 14, 2015 in Los Angeles, California. (Photo by Joe Scarnici/WireImage)
LOS ANGELES, CA - JUNE 14: Actor Mark Ruffalo attends the premiere of 'Infinitely Polar Bear' at the 2015 Los Angeles Film Festival at Regal Cinemas L.A. Live on June 14, 2015 in Los Angeles, California. (Photo by Jason LaVeris/FilmMagic)
BEVERLY HILLS, CA - NOVEMBER 05: Actor Mark Ruffalo speaks onstage during the Screen Actors Guild Foundation 30th Anniversary Celebration at Wallis Annenberg Center for the Performing Arts on November 5, 2015 in Beverly Hills, California. (Photo by Mark Davis/Getty Images for Screen Actors Guild Foundation)
BEVERLY HILLS, CA - NOVEMBER 05: Honoree Leonardo DiCaprio (L) and actor Mark Ruffalo attend the Screen Actors Guild Foundation 30th Anniversary Celebration at Wallis Annenberg Center for the Performing Arts on November 5, 2015 in Beverly Hills, California. (Photo by Angela Weiss/Getty Images for Screen Actors Guild Foundation)
NEW YORK, NY - NOVEMBER 30: Sunrise Coigney and Mark Ruffalo attend the 2015 Gotham Independent Film Awards at Cipriani Wall Street on November 30, 2015 in New York City. (Photo by Taylor Hill/Getty Images)
HOLLYWOOD, CA - NOVEMBER 14: Sunrise Coigney and Mark Ruffalo attend the Academy of Motion Picture Arts and Sciences' 7th Annual Governors Awards at The Ray Dolby Ballroom at Hollywood & Highland Center on November 14, 2015 in Hollywood, California. (Photo by Araya Diaz/WireImage)
LONDON, ENGLAND - FEBRUARY 14: Sunrise Coigney and Mark Ruffalo attend the EE British Academy Film Awards at the Royal Opera House on February 14, 2016 in London, England. (Photo by Ian Gavan/Getty Images)
LOS ANGELES, CA - FEBRUARY 24: Actors Sunrise Coigney (L) and Mark Ruffalo attend Vanity Fair and Barneys New York Private Dinner Celebrating 'Spotlight' Director Tom McCarthy at Chateau Marmont on February 24, 2016 in Los Angeles, California. (Photo by Jonathan Leibson/Getty Images for Vanity Fair)
NEW YORK, NY - APRIL 18: Mark Ruffalo attends the Tribeca Talks Directors Series: Joss Whedon With Mark Ruffalo - 2016 Tribeca Film Festival at SVA Theatre on April 18, 2016 in New York City. (Photo by Daniel Zuchnik/Getty Images)
NEW YORK, NY - MAY 02: Actor Mark Ruffalo attends New Yorkers for Clean Power campaign launch at Solar 1 on May 2, 2016 in New York City. (Photo by Mireya Acierto/FilmMagic)
NEW YORK, NY - JUNE 06: Actor Mark Ruffalo attends Summit Entertainment presents the world premiere of 'Now You See Me 2' at AMC Loews Lincoln Square on June 6, 2016 in New York City. (Photo by Jimi Celeste/Patrick McMullan via Getty Images)
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Ruffalo and Bomer starred in HBO's "The Normal Heart," in which Bomer plays Ruffalo's love interest. Bomer won a Golden Globe for the film.

When news broke that Bomer, a cisgender but openly gay actor, would play the transgender role in the film, people took to Twitter to express their frustration that a real trans woman wasn't cast in the film.

Some even called for Bomer's role to be recast, but Ruffalo revealed the film had already wrapped.

"The movie is already shot and Matt poured his heart and soul into this part," said Ruffalo. "Please have a little compassion. We are all learning."

Other cisgender actors who have played transgender characters include Eddie Redmayne in "The Danish Girl," Jared Leto in "Dallas Buyers Club" and Jeffrey Tambor in "Transparent."

"Anything" was written and directed by Timothy McNeil. The film does not have a release date yet.

Read original story Mark Ruffalo Responds to Criticism of Matt Bomer's Transgender Role in 'Anything' At TheWrap

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