Nickelodeon's 'Loud House' to feature network's first married same-sex couple

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Nickelodeon's Loud House is about to make history.

For the first time in the history of the Viacom-owned cable network, one of its original animated series will introduce a same-sex married couple, The Hollywood Reporter has confirmed.

In the episode set to air Wednesday, the biracial gay couple are the parents of Clyde McBride and are voiced by Michael McDonald and Wayne Brady.

The Loud House, which debuted on the channel in May, centers on the life of Lincoln Loud and his 10 sisters. Clyde is Lincoln's best friend and a main character on the series.

Photo cred: Nickeldeon

A clip from the episode, which airs Wednesday at 5 p.m., was first posted to Twitter on Saturday. As seen in the clip, Clyde's parents pop up when they drop off their son for a sleepover.

Disney Channel broke similar barriers in 2014 when live-action comedy Good Luck Charlie introduced a same-sex couple in 2014.

More from one Nickelodeon star, Amanda Bynes, in the gallery below.

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Amanda Bynes
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Amanda Bynes
LOS ANGELES, CA - AUGUST 25: Amanda Bynes is seen on August 25, 2015 in Los Angeles, California. (Photo by Bauer-Griffin/GC Images)
LOS ANGELES, CA - JULY 23: Former actress Amanda Bynes attends the Michael Costello and Style PR Capsule Collection launch party on July 23, 2015 in Los Angeles, California. (Photo by David Livingston/Getty Images)
NEW YORK, NY - OCTOBER 06: Amanda Bynes attends NYLON Magazine's IT Girl Party at Gilded Lily on October 6, 2014 in New York City. (Photo by Astrid Stawiarz/Getty Images for NYLON)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen doing her make-up outside in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen doing her make-up outside in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
LOS ANGELES, CA - OCTOBER 10: Amanda Bynes is seen at LAX on October 10, 2014 in Los Angeles, California. (Photo by GVK/Bauer-Griffin/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen doing her make-up outside in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen doing her make-up outside in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen doing her make-up outside in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Actress Amanda Bynes is seen with friends in Soho on October 6, 2014 in New York City. (Photo by Raymond Hall/GC Images)
NEW YORK, NY - OCTOBER 06: Amanda Bynes attends NYLON Magazine's IT Girl Party at Gilded Lily on October 6, 2014 in New York City. (Photo by Astrid Stawiarz/Getty Images for NYLON)
NEW YORK, NY - JULY 09: Actress Amanda Bynes attends an appearance at Manhattan Criminal Court on July 9, 2013 in New York City. Bynes is facing charges of reckless endangerment, tampering with evidence and criminal possession of marijuana in relation to her arrest on May 23, 2013. (Photo by Raymond Hall/FilmMagic)
WEST HOLLYWOOD, CA - APRIL 06: In this handout image provided by the Los Angeles County Sheriff's Office, actress Amanda Bynes is seen in a police booking photo April 6, 2012 in West Hollywood, California. Bynes was arrested for driving under the influence of alcohol. (Photo by Los Angeles County Sheriff's Office via WireImage)
NEW YORK, NY - MAY 24: Actress Amanda Bynes departs Manhattan Central Booking after being arrested on May 23 2013 for alleged charges of reckless endangerment, tampering with evidence and criminal possession of marijuana at Manhattan Criminal Court on May 24, 2013 in New York City. (Photo by Alo Ceballos/Getty Images)
NEW YORK, NY - JULY 10: Amanda Bynes as seen on July 10, 2013 in New York City. (Photo by NCP/Star Max/FilmMagic)
NEW YORK, NY - JULY 09: Amanda Bynes sighted on July 9, 2013 in Midtown, New York City. Bynes earlier appeared at Manhattan Criminal Court to face charges of reckless endangerment, tampering with evidence and criminal possession of marijuana in relation to her arrest on May 23, 2013. (Photo by Alo Ceballos/FilmMagic)
NEW YORK, NY - JULY 09: Actress Amanda Bynes attends an appearance at Manhattan Criminal Court on July 9, 2013 in New York City. Bynes is facing charges of reckless endangerment, tampering with evidence and criminal possession of marijuana in relation to her arrest on May 23, 2013. (Photo by Raymond Hall/FilmMagic)
NEW YORK, NY - JULY 09: Actress Amanda Bynes enters Manhattan Criminal Court on July 9, 2013 in New York City. Bynes is facing charges of reckless endangerment, tampering with evidence and criminal possession of marijuana in relation to her arrest on May 23, 2013. (Photo by Ray Tamarra/Getty Images)
NEW YORK, NY - JULY 09: Amanda Bynes arrives for an appearance at Manhattan Criminal Court on July 9, 2013 in New York City. Bynes is facing charges of reckless endangerment, tampering with evidence and criminal possession of marijuana in relation to her arrest on May 23, 2013. (Photo by Dave Kotinsky/Getty Images)
BEVERLY HILLS, CA - MAY 14: Amanda Bynes leaves the Neil George Salon on May 14, 2009 in Beverly Hills, California. (Photo by OutOfSightMedia/BuzzFoto/FilmMagic)
UNIVERSAL CITY, CA - JUNE 05: Amanda Bynes attends the 2011 MTV Movie Awards on June 5, 2011 in Universal City, California. (Photo by Steve Granitz/WireImage)
LAS VEGAS - OCTOBER 03: Actress Amanda Bynes arrives at the Tao Nightclub at the Venetian Resort Hotel Casino during the club's four-year anniversary party October 3, 2009 in Las Vegas, Nevada. (Photo by Ethan Miller/Getty Images)
Actress Amanda Bynes arrives at the 2011 MTV Movie Awards at Gibson Amphitheatre on June 5, 2011 in Universal City, California. (Photo by Jon Kopaloff/FilmMagic)
Amanda Bynes and Frankie Muniz at the 11th Annual Elizabeth Glaser Pediatric Aids Foundation's 'A Time For Heroes' carnival and picnic at Ken Robert's estate in Mandeville Canyon, Los Angeles, Ca.
Actress Amanda Bynes, right, smiles after receiving the Favorite Television Actress award from singer Mandy Moore, left, during Nickelodeon's 15th annual Kids' Choice Awards in Santa Monica, Calif., Saturday, April 20, 2002. (AP Photo/Lucy Nicholson)
Kelly Preston, left, Amanda Bynes and Oliver James pose at the premiere of 'What A Girl Wants' in Hollywood, Calif., on Thursday, March 27, 2003. (AP Photo/Chris Polk)
Actress Amanda Bynes is joined by her co-star Oliver James, as she blows out candles on a birthday cake bearing an American flag and British Union Jack, at the party following the New York premiere of her movie "What A Girl Wants," to benefit The Rainforest Alliance, Wednesday night April 2, 2003. Bynes turns 17 Thursday April 3. (AP Photo/Richard Drew)
UNIVERSAL CITY, CA - AUGUST 14: Actress Amanda Bynes poses in the press room at the 2005 Teen Choice Awards held at Gibson Amphitheatre at Universal CityWalk on August 14, 2005 in Universal City, California. (Photo by Frazer Harrison/Getty Images)
Amanda Bynes during What A Girl Wants Cast Members Appear At Planet Hollywood at Planet Hollywood in New York, New York, United States. (Photo by Lawrence Lucier/FilmMagic)
Amanda Bynes during 5th Annual Lullabies and Luxuries Luncheon and Fashion Show Benefitting Caring For Children and Families With AIDS at Regent Beverly Wilshire Hotel in Beverly Hills, California, United States. (Photo by Jon Kopaloff/FilmMagic)
UNIVERSAL CITY, CA - AUGUST 14: Actors Shawn Wayans, Amanda Bynes and Marlon Wayans present an award onstage at the 2005 Teen Choice Awards held at Gibson Amphitheatre at Universal CityWalk on August 14, 2005 in Universal City, California. (Photo by Kevin Winter/Getty Images)
Actress Amanda Bynes co-hosts MTV's "Total Request Live" show at the MTV Times Square Studios, Thursday, March 16, 2006 in New York. Bynes is the star of the film "She's the Man" which opens March 17 nationwide. (AP Photo/Jeff Christensen)
Actress Amanda Bynes holds her trophy during a taping for MTV's "Total Request Live Awards" show at the MTV Times Square Studios, Tuesday, Feb.21, 2006 in New York City. (AP Photo/Jeff Christensen)
MIAMI - FEBRUARY 06: Vanessa Minnillo and Amanda Bynes attend The Maxim Party 2010 at The Raleigh on February 6, 2010 in Miami, Florida. (Photo by Vallery Jean/Getty Images for Maxim)
MIAMI - FEBRUARY 06: Actress Amanda Bynes attends The Maxim Party 2010 at The Raleigh on February 6, 2010 in Miami, Florida. (Photo by Vallery Jean/Getty Images for Maxim)
NEW YORK - SEPTEMBER 17: Amanda Bynes attends the Ann Taylor Fall 2009 'See Now, Wear Now' Runway Show at the New York Public Library - Celeste Bartos Forum on September 17, 2009 in New York City. (Photo by Slaven Vlasic/WireImage for Shadow PR)
NEW YORK - SEPTEMBER 13: Actress Amanda Bynes attends the 2009 MTV Video Music Awards at Radio City Music Hall on September 13, 2009 in New York City. (Photo by Jeffrey Mayer/WireImage)
NEW YORK - SEPTEMBER 13: Actress Amanda Bynes at Bryant Park on September 13, 2009 in New York City. (Photo by Gustavo Caballero/Getty Images)
NEW YORK - SEPTEMBER 13: Actor Amanda Bynes poses for a picture at the 2009 MTV Video Music Awards at Radio City Music Hall on September 13, 2009 in New York City. (Photo by Christopher Polk/Getty Images)
NEW YORK - SEPTEMBER 13: Actress Amanda Bynes (L) poses with designer Max Azria at the Herve Leger Spring 2010 Fashion Show at the Promenade at Bryant Park on September 13, 2009 in in New York City. (Photo by Bryan Bedder/Getty Images for Herve Leger)
NEW YORK - SEPTEMBER 10: Lyn Collins, actress Amanda Bynes, actress Joanna Garcia and singer Solange Knowles attend the BCBG Max Azria Spring 2010 Fashion Show at the Tent during Mercedes-Benz Fashion Week at Bryant Park on September 10, 2009 in New York, New York. (Photo by Astrid Stawiarz/Getty Images for BCBG Max Azria)
NEW YORK - SEPTEMBER 12: Actress Hilary Duff and Actress Amanda Bynes are seen around Bryant Park on September 12, 2009 in New York City. (Photo by John Parra/WireImage)
NEW YORK - SEPTEMBER 12: Amanda Bynes and Kelly Rutherford attend the QVC Style Live celebration during Mercedes-Benz Fashion Week Spring 2010 at Bryant Park on September 12, 2009 in New York City. (Photo by Johnny Nunez/WireImage)
UNIVERSAL CITY, CA - AUGUST 09: Actress Amanda Bynes arrives at the Teen Choice Awards 2009 held at the Gibson Amphitheatre on August 9, 2009 in Universal City, California. (Photo by Steve Granitz/WireImage)
June 6, 2009 Brentwood, Ca.; Amanda Bynes; 8th Annual Chrysalis Butterfly Ball; Held at a Private Residence (Photo by Gregg DeGuire/FilmMagic)
CENTURY CITY, CA - MAY 08: Actresses Angie Harmon and Amanda Bynes attend the 16th Annual Race To Erase MS cocktail reception co-chaired by Nancy Davis and Tommy Hilfiger at the Hyatt Regency Century Plaza on May 8, 2009 in Century City, California. (Photo by Kevin Winter/WireImage)
CENTURY CITY, CA - MAY 08: Actress Amanda Bynes attends the 16th Annual Race To Erase MS cocktail reception co-chaired by Nancy Davis and Tommy Hilfiger at the Hyatt Regency Century Plaza on May 8, 2009 in Century City, California. (Photo by Kevin Winter/WireImage)
CENTURY CITY, CA - MAY 08: Actress Amanda Bynes arrives at the 16th Annual Race to Erase MS event co-chaired by Nancy Davis and Tommy Hilfiger at Hyatt Regency Century Plaza on May 8, 2009 in Century City, California. (Photo by Steve Granitz/WireImage)
NEW YORK, NY - JULY 10: Amanda Bynes as seen on July 10, 2013 in New York City. (Photo by NCP/Star Max/FilmMagic)
NEW YORK, NY - JULY 10: Amanda Bynes is seen in Chelsea on July 10, 2013 in New York City. (Photo by Alo Ceballos/FilmMagic)
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