Coca-Cola is one of Berkshire's "big four" investments, and Buffett has been a fervent ambassador of the company's flagship soda over the years.
But he has been criticized for investing in Coca-Cola because of the health risks that excessive soda consumption pose.
During the Q&A session, CNBC's Andrew Ross Sorkin forwarded a shareholder question on why Berkshire investors should be proud to own a stake in Coca-Cola. He prefaced it with a number of stats about the dangers of soda.
Warren Buffett through the years:
Warren Buffett through the years
BUFFETT: I haven't seen proof that I'm more likely to reach 100 if I stop drinking Coke
Warren Buffett speaks to the media during a press conference Monday, June 26, 2006 in New York. Buffet, the chairman of Berkshire Hathaway, recently announced his intention of giving 10 million shares of his company to charitable organizations, the majority going to the Bill and Melinda Gates Foundation. (AP Photo/Seth Wenig)
NEW YORK, UNITED STATES: California Governor Arnold Schwarzenegger (L) cofers with billionaire investor Warren Buffet (R) during a meeting with Wall Street investors at the Ritz Carlton hotel February 25, 2004 in New York City. AFP PHOTO/POOL/Kathy WILLENS (Photo credit should read KATHY WILLENS/AFP/Getty Images)
Investor Warren Buffet participates in the Treasury Conference on U.S. Capital Markets Competitiveness, Tuesday, March 13, 2007, at Georgetown University in Washington. (AP Photo/Gerald Herbert)
CLEVELAND - MARCH 25: Philanthropist Warren Buffet (C) wears a LeBron James Witness tee-shirt as he cheers for the Cleveland Cavaliers during a game against the Denver Nuggets March 25, 2007 at The Quicken Loans Arena in Cleveland, Ohio. NOTE TO USER: User expressly acknowledges and agrees that, by downloading and/or using this Photograph, user is consenting to the terms and conditions of the Getty Images License Agreement. Mandatory Copyright Notice: Copyright 2007 NBAE (Photo by David Liam Kyle/NBAE via Getty Images)
** FILE ** In this May 21, 2008 file photo, U.S. Billionaire investor Warren Buffet speaks during a news conference in Madrid. Buffett's Berkshire Hathaway Inc. is investing at least $5 billion in Goldman Sachs Group Inc., Goldman announced Tuesday, Sept. 23, 2008. (AP Photo/Paul White, file)
Warren Buffet, chairman of Bershire Hathaway, arrives for the annual Allen & Co.'s media conference Wednesday, July 9, 2008, in Sun Valley, Idaho. (AP Photo/Douglas C. Pizac)
FILE - In this May 2, 2009 file photo, Warren Buffett, CEO of Berkshire Hathaway, right, waves to shareholders prior to the annual Berkshire Hathaway shareholders meeting in Omaha, Neb. Warren Buffet's Berkshire Hathaway said Tuesday, Nov. 3, 2009, it has agreed to buy Burlington Northern Santa Fe in a deal valuing the railroad at $34 billion.(AP Photo/Nati Harnik, file)
Warren Buffet heads to lunch after a morning session at the Sun Valley Inn for the 2011 Allen and Co. Sun Valley Conference, Thursday, July 7, 2011, in Sun Valley, Idaho. (AP Photo/Julie Jacobson)
Warren Buffett is interviewed in the White House Briefing Room in Washington, Monday, July 18, 2011, following his meeting with President Barack Obama. Obama met with members of the Giving Pledge including, Buffett and Bill and Melinda Gates, and others to receive and update on the program. (AP Photo/Pablo Martinez Monsivais)
Billionaire investor Warren Buffet at the Allen & Company Sun Valley Conference in Sun Valley, Idaho, Friday, July 13, 2012. (AP Photo/Paul Sakuma)
Warren Buffett, chairman of Berkshire Hathaway Inc., right, speaks to David Rubenstein, co-founder and managing director of the Carlyle Group, during the Economic Club of Washington dinner event in Washington, D.C., U.S., on Tuesday, June 5, 2012. Buffett said he doesn't expect another U.S. recession unless Europe's crisis spreads. Photographer: Andrew Harrer/Bloomberg via Getty Images
DETROIT, MI - SEPTEMBER 18: Billionaire investor Warren Buffett speaks at an event called, 'Detroit Homecoming' September 18, 2014 in Detroit, Michigan. The purpose of the invitation-only event of Detroit expatriats is to give the group a chance to reconnect, reinvest and reinvent with their hometown. The topic of Buffet's conversation was, 'Why I'm Bullish on Detroit.' (Photo by Bill Pugliano/Getty Images)
Warren E. Buffett, Chairman of the Board and Chief Executive Officer, Berkshire Hathaway Inc., participates in a NADA Automotive forum happening in conjunction with the New York International Auto Show, Tuesday, March 31, 2015, in New York. (AP Photo/Mary Altaffer)
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"I have not seen evidence that convinces me that I'll make it, that it will be more likely that I reach 100 if I suddenly switch to water and broccoli," Buffett said.
He is 85.
He said in terms of daily calorie consumption, he didn't see anything off about having 2,700 or 2,800 out of 3,500 calories come from Coke.
Buffett said he found from Census Bureau figures that roughly 10,000 men in the US that lived to be 100 years old or greater, compared to roughly 45,000 women.
"So if you really want to improve your longevity prospects — I mean, a guy in my position — you have a sex change."
As Myles Udland pointed out, it seems Buffett is tired of answering this question at this point.
"I really wish I'd had a twin, and that twin had eaten broccoli his entire life, and we both consumed the same number of calories," Buffett said. "I know I would have been happier, and I think the odds are fairly good that I would've lived longer. I think Coca-Cola is a marvelous product."
Buffett has even gotten heat from Pershing Square's Bill Ackman, who said Coca-Cola damages society just as Munger accused Valeant Pharmaceuticals — which Ackman owns shares of — of being immoral. Some people even speculated that Ackman planted the question.
Berkshire vice chairman Charlie Munger also chipped in. He was drinking diet Coke from a wine glass during the Q&A.
Munger also seemed a little frustrated with the question, and said people who ask it all the time don't mention the upside.