Hillary Clinton wins South Carolina primary

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Hillary Clinton scored another major victory in the fight for the Democratic presidential nomination, winning the South Carolina primary over rival Bernie Sanders on Saturday.

Multiple networks called the race for Clinton shortly after polls in the state closed at 7 p.m. EST, with NBC dubbing Clinton's win "overwhelming."

As of 8:20 p.m. EST, Clinton led Sanders, the Vermont senator, 75% to 24.3%, with about 40% of precincts reporting.

Click through images of Clinton campaigning in South Carolina:

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Hillary Clinton South Carolina campaign
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Hillary Clinton wins South Carolina primary
CHARLESTON, SC - Former Secretary of State Hillary Clinton visits a South Carolina Strong non profit facility for former felons in North Charleston, South Carolina on Wednesday February 24, 2016. (Photo by Melina Mara/The Washington Post via Getty Images)
CHARLESTON, SC - FEBRUARY 24: Democratic Presidential candidate, former Secretary of State Hillary Clintongreets supporters after visiting the International Longshoremen's Association Local 1422 February 24, 2016 in North Charleston, ahead of the South Carolina Democratic Presidential Primary on February 27. Last Saturday, the South Carolina GOP Presidential Primary shattered records with 137,092 more votes cast than in any previous primary. (Photo by Mark Makela/Getty Images)
NORTH CHARLESTON, SC - FEBRUARY 24: Democratic Presidential candidate, former Secretary of State Hillary Clinton slips as she walks up the stairs into the non-profit SC Strong, a 2 year residential facility that helps former felons, substance abusers, and homeless move into self-sufficiency February 24, 2016 in North Charleston. The South Carolina Democratic Presidential Primary is held on February 27. (Photo by Mark Makela/Getty Images)
CHARLESTON, SC - Former Secretary of State Hillary Clinton visits a South Carolina Strong non profit facility for former felons in North Charleston, South Carolina on Wednesday February 24, 2016. (Photo by Melina Mara/The Washington Post via Getty Images)
CHARLESTON, SC - FEBRUARY 24: Democratic Presidential candidate, former Secretary of State Hillary Clintongreets supporters after visiting the International Longshoremen's Association Local 1422 February 24, 2016 in North Charleston, ahead of the South Carolina Democratic Presidential Primary on February 27. Last Saturday, the South Carolina GOP Presidential Primary shattered records with 137,092 more votes cast than in any previous primary. (Photo by Mark Makela/Getty Images)
CHARLESTON, SC - FEBRUARY 24: Democratic Presidential candidate, former Secretary of State Hillary Clinton visits the International Longshoremen's Association Local 1422 February 24, 2016 in North Charleston, ahead of the South Carolina Democratic Presidential Primary on February 27. Last Saturday, the South Carolina GOP Presidential Primary shattered records with 137,092 more votes cast than in any previous primary. (Photo by Mark Makela/Getty Images)
NORTH CHARLESTON, SC - FEBRUARY 24: Democratic Presidential candidate former Secretary of State Hillary Clinton visits the non-profit SC Strong, a 2 year residential facility that helps former felons, substance abusers, and homeless move into self-sufficiency February 24, 2016 in North Charleston. The South Carolina Democratic Presidential Primary is held on February 27. (Photo by Mark Makela/Getty Images)
CHARLESTON, SC - Former Secretary of State Hillary Clinton visits a South Carolina Strong non profit facility for former felons in North Charleston, South Carolina on Wednesday February 24, 2016. (Photo by Melina Mara/The Washington Post via Getty Images)
CHARLESTON, SC - FEBRUARY 24: Democratic Presidential candidate, former Secretary of State Hillary Clintongreets supporters after visiting the International Longshoremen's Association Local 1422 February 24, 2016 in North Charleston, ahead of the South Carolina Democratic Presidential Primary on February 27. Last Saturday, the South Carolina GOP Presidential Primary shattered records with 137,092 more votes cast than in any previous primary. (Photo by Mark Makela/Getty Images)
CHARLESTON, SC - Former Secretary of State Hillary Clinton visits a South Carolina Strong non profit facility for former felons in North Charleston, South Carolina on Wednesday February 24, 2016. (Photo by Melina Mara/The Washington Post via Getty Images)
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Shortly after the polls closed, the secretary thanked her supporters in South Carolina, signing the tweet with her first initial.

"To South Carolina, to the volunteers at the heart of our campaign, to the supporters who power it: thank you. -H," Clinton tweeted.

"Tomorrow, this campaign goes national," she said in a victory speech to supporters a little while later.

The results represented the second consecutive loss for Sanders, the independent senator from Vermont, who was not able to crumble Clinton's strong hold on the Palmetto State.

Sanders appeared to recognize he could not win the state. He spent some of the week in South Carolina, but left mid-week to make campaign stops in several other states, including Oklahoma.

Clinton's victory comes as the primary map improves significantly for her heading into next week's Super Tuesday contests.

Recent polls show Clinton edging Sanders in crucial states set to hold their primaries and caucuses next week. It could award her a sizeable chunk of the 2,383 delegates needed to secure the Democratic presidential nomination.

But there are still warning signs for Democrats as a whole.

Like Iowa and Nevada, some early reports found Democratic voter turnout in South Carolina would likely fall far short of 2008. Republican primary voters and caucus-goers have shattered turnout records in almost every contest thus far, a sign to some experts that voter enthusiasm is higher among GOP voters.

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