'The World Trade Center came down': Donald Trump and Jeb Bush unload on each other in explosive debate exchange

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Donald Trump and former Florida Gov. Jeb Bush (R) faced off over foreign policy at the CBS News Republican debate on Saturday night in what became an explosive early exchange.

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Moderator John Dickerson pointed out that Trump has said he would work with Russia as the country gets involved in Syria, ostensibly to fight the terrorist group ISIS.

Trump then negated Bush's stance on Russia not being an ally of the US, saying that "Jeb is so wrong" in his assessment.

Click through reactions to the debate here:

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'The World Trade Center came down': Donald Trump and Jeb Bush unload on each other in explosive debate exchange
Can @johnkasich get away with going ruthlessly positive? #GOPDebate
Trump raised a key Q right from the beginning-- "Does the GOP exist independently from the Bushes and the Bush legacy?"
This audience sounds like Jerry Springer! This is embarrassing. #CBSDebate #GOPDebate
Lincon-Douglas this is not. #CBSDebate
Trump treads a fine line in renouncing the Iraq war. #CBSDebate
Kasich sounding like he's rehashing McCain's "community of democracies" idea. #GOPDebate
Carson says no political background is not a liability. better judgment, not experience, is necessary. @RealBenCarson #GOPDebate
#GOPDebate opening with moment of silence for Justice #Scalia.
Ah yes, the article in the Constitution that outlines "Congress shall delay delay delay."
Ted is crushing it. #GOPDebate
#GOPDebate Clearly Republicans do not like a moderator who wants to "get the facts straight."
Lol, perfect. #gopdebate audience literally booing facts.
Good answer from Rubio on foreign policy #GOPDebate
Rubio is an expert in foreign policy. Makes Trump look like an idiot. #GOPDebate
Carson its time to exit sir. #GOPDebate
who is Trump calling a lobbyist? #GOPDebate
Why is Trump screaming? #GOPDebate #CBSDebate
Trump is right. Bush made security worse for America. #bigfatmistake #CBSDebate
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Bush retorted that Russian President Vladimir Putin wouldn't be an ally of the US and pointed out that Russian planes are attacking US allies in Syria. He called for a Sunni-led coalition on the ground to destroy ISIS.

"We're supporting troops that we don't even know who they are," Trump said, repeating the line. "We have no idea who they are."

Dickerson cut in and tried to move on, but Bush shot back at Trump.

"This is from a guy who gets his foreign policy from the shows," he said. "This is a guy who thinks that Hillary Clinton is a great negotiator in Iran. We're living in dangerous times. This is a man who insults his way to the nomination."

Trump started talking over him.

"He spent $24 million in New Hampshire and he's practically ... $24 million in New Hampshire," Trump said. "Give me a break!"

Dickerson cut in again.

"Gentlemen, let's leave it there so I can ask a question of Sen. Cruz, who is also running for president," he said, referring to Sen. Ted Cruz (R-Texas).

But it wasn't over there.

After Cruz answered a question, Bush and Trump went at it again. Dickerson asked Trump about former President George W. Bush campaigning for Jeb in South Carolina, mentioning that Trump has said that the former president should have been "impeached" for getting the US into the Iraq War.

"Obviously the war in Iraq was a big, fat mistake," Trump said. He then attacked Jeb Bush for waffling earlier in the campaign on whether the war was a mistake.

"It took him five days before his people told him what to say, and ultimately he said it was a mistake," Trump said.

Jeb then said that he was "sick and tired" of President Barack Obama blaming George W. Bush, his brother, for the "problems that he's had."

He continued: "I could care less about the insults that Donald Trump gives to me. It's blood sport for him, he enjoys it, and I'm glad he's happy about it. But I am sick and tired, I am sick and tired of him going after my family. My dad [former President George H. W. Bush] is the greatest man alive in my mind. While Donald Trump was building a reality TV show, my brother was building a security apparatus to keep us safe. And I'm proud of what he did."

"The World Trade Center came down during your brother's reign," Trump retorted. "Remember that."

The crowd booed loudly.

While Jeb was saying that Trump has "had the gall" to go after his mother, Trump talked over him.

"That's not keeping us safe," Trump said, continuing his point.

Jeb continued talking about his family, saying that his mother is the strongest woman he knows.

"She should be running," Trump replied.

More from Saturday night's debate:

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CBS News - GOP Debate in South Carolina
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'The World Trade Center came down': Donald Trump and Jeb Bush unload on each other in explosive debate exchange
Republican presidential candidates, from left, Ohio Gov. John Kasich, former Florida Gov. Jeb Bush, Sen. Ted Cruz, R-Texas, businessman Donald Trump, Sen. Marco Rubio, R-Fla., retired neurosurgeon Ben Carson take the stage before the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidates, from left, Ohio Gov. John Kasich, former Florida Gov. Jeb Bush, Sen. Ted Cruz, R-Texas, businessman Donald Trump, Sen. Marco Rubio, R-Fla., retired neurosurgeon Ben Carson participate during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidate, former Florida Gov. Jeb Bush poses for a photograph after the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidates Ted Cruz (L)and Marco Rubio (R) applaud as fellow candidate Donald Trump (C) is introduced during the CBS News Republican Presidential Debate in Greenville, South Carolina, February 13, 2016. / AFP / JIM WATSON (Photo credit should read JIM WATSON/AFP/Getty Images)
GREENVILLE, SC - FEBRUARY 13: Republican presidential candidates (L-R) Donald Trump and Sen. Marco Rubio (R-FL) participate in a CBS News GOP Debate February 13, 2016 at the Peace Center in Greenville, South Carolina. Residents of South Carolina will vote for the Republican candidate at the primary on February 20. (Photo by Spencer Platt/Getty Images)
Republican presidential candidate, Sen. Marco Rubio, R-Fla., right, right, speaks to Republican presidential candidate, businessman Donald Trump during a commercial break during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
GREENVILLE, SC - FEBRUARY 13: Republican presidential candidate Ohio Governor John Kasich participates in a CBS News GOP Debate February 13, 2016 at the Peace Center in Greenville, South Carolina. Residents of South Carolina will vote for the Republican candidate at the primary on February 20. (Photo by Spencer Platt/Getty Images)
Republican presidential candidate, businessman Donald Trump speaks during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidate, Ohio Gov. John Kasich, left, speaks as Republican presidential candidate, former Florida Gov. Jeb Bush listens during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidate, former Florida Gov. Jeb Bush responds to Republican presidential candidate, businessman Donald Trump during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidate, businessman Donald Trump speaks during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidates, from left, Ohio Gov. John Kasich, former Florida Gov. Jeb Bush, Sen. Ted Cruz, R-Texas, businessman Donald Trump, Sen. Marco Rubio, R-Fla., retired neurosurgeon Ben Carson participate during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidate Marco Rubio gives a thumbs up after the CBS News Republican Presidential Debate in Greenville, South Carolina, February 13, 2016. / AFP / JIM WATSON (Photo credit should read JIM WATSON/AFP/Getty Images)
Republican presidential candidate, Sen. Ted Cruz, R-Texas, speaks during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidate, Sen. Marco Rubio, R-Fla., right, speaks with Republican presidential candidate, businessman Donald Trump during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Republican presidential candidates, from left, Ohio Gov. John Kasich, former Florida Gov. Jeb Bush, Sen. Ted Cruz, R-Texas, businessman Donald Trump, Sen. Marco Rubio, R-Fla., retired neurosurgeon Ben Carson participate during the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
Ben Carson, retired neurosurgeon and 2016 Republican presidential candidate, speaks during the Republican presidential candidate debate sponsored by CBS News and the Republican National Committee at the Peace Center in Greenville, South Carolina, U.S., on Saturday, Feb. 13, 2016. Donald Trump tops the GOP field with support from 36.3 percent of likely South Carolina Republican primary voters with Ted Cruz at 19.6 percent, according to a poll conducted for the Augusta Chronicle released on Friday. Photographer: Daniel Acker/Bloomberg via Getty Images
GREENVILLE, SC - FEBRUARY 13: Republican presidential candidates Ben Carson (R) listens to a TV crew member as Donald Trump (L) smiles during a break of a CBS News GOP Debate February 13, 2016 at the Peace Center in Greenville, South Carolina. Residents of South Carolina will vote for the Republican candidate at the primary on February 20. (Photo by Spencer Platt/Getty Images)
Republican presidential candidate, Sen. Marco Rubio, R-Fla., kisses his wife Jeanette Dousdebes Rubio after the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/John Bazemore)
2016 Republican Presidential candidates Donald Trump, president and chief executive of Trump Organization Inc., from left, Senator Marco Rubio, a Republican from Florida, and Ben Carson, retired neurosurgeon, stand on stage at the start of the Republican presidential candidate debate sponsored by CBS News and the Republican National Committee at the Peace Center in Greenville, South Carolina, U.S., on Saturday, Feb. 13, 2016. Donald Trump tops the GOP field with support from 36.3 percent of likely South Carolina Republican primary voters with Ted Cruz at 19.6 percent, according to a poll conducted for the Augusta Chronicle released on Friday. Photographer: Daniel Acker/Bloomberg via Getty Images
Republican presidential candidate, businessman Donald Trump speaks to the media in the spin room after the CBS News Republican presidential debate at the Peace Center, Saturday, Feb. 13, 2016, in Greenville, S.C. (AP Photo/Rainier Ehrhardt)
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