Scientists are trying to use genetically engineered mosquitoes to stop the rapidly-spreading Zika virus

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What You Need to Know About the Potential Zika Virus Outbreak

A virus that until this month had never been in the US has been connected to a case of brain abnormality in Hawaii.

The mosquito-borne Zika virus is causing severe problems in Brazil, where it appears to be connected to serious birth defects.

To stop Zika's spread, a company called Oxitec is planning on expanding its genetically-engineered mosquito project to try to rid areas in Brazil of the bug at the heart of the problem: the Aedes aegypti mosquito.

Learn more about the Zika virus:

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Scientists are trying to use genetically engineered mosquitoes to stop the rapidly-spreading Zika virus
Aedes aegypti mosquitos are seen in containers at a lab of the Institute of Biomedical Sciences of the Sao Paulo University, on January 8, 2016 in Sao Paulo, Brazil. Researchers at the Pasteur Institute in Dakar, Senegal are in Brazil to train local researchers to combat the Zika virus epidemic. / AFP / NELSON ALMEIDA (Photo credit should read NELSON ALMEIDA/AFP/Getty Images)
Female Aedes aegypti mosquitoes are kept in a container at the Biomedical Sciences Institute in the Sao Paulo's University, in Sao Paulo, Brazil, Monday, Jan. 18, 2016. The Aedes aegypti is a vector for transmitting the Zika virus. The Brazilian government announced it will direct funds to a biomedical research center to help develop a vaccine against the Zika virus linked to brain damage in babies. (AP Photo/Andre Penner)
A female Aedes aegypti mosquito acquires a blood meal on the arm of a researcher at the Biomedical Sciences Institute in the Sao Paulo's University, in Sao Paulo, Brazil, Monday, Jan. 18, 2016. The Aedes aegypti is a vector for transmitting the Zika virus. The Brazilian government announced it will direct funds to a biomedical research center to help develop a vaccine against the Zika virus linked to brain damage in babies. (AP Photo/Andre Penner)
CORRECTS CDC IS INVESTIGATING WHETHER AEDES ALBOPICTUS SPREADS THE ZIKA VIRUS, NOT DEFINITIVE - This 2003 photo provided by the Centers for Disease Control and Prevention shows a female Aedes albopictus mosquito acquiring a blood meal from a human host. On Friday, Jan. 15, 2016, U.S. health officials are telling pregnant women to avoid travel to Latin America and Caribbean countries with outbreaks of a tropical illness linked to birth defects. The Zika virus is spread through mosquito bites from Aedes aegypti and the CDC is investigating whether it is also spread by Aedes albopictus. The disease causes only a mild illness in most people. But thereâs been mounting evidence linking the virus to a surge of a rare birth defect in Brazil. (James Gathany/Centers for Disease Control and Prevention via AP)
A researcher holds a container with female Aedes aegypti mosquitoes at the Biomedical Sciences Institute in the Sao Paulo's University, in Sao Paulo, Brazil, Monday, Jan. 18, 2016. The Aedes aegypti is a vector for transmitting the Zika virus. The Brazilian government announced it will direct funds to a biomedical research center to help develop a vaccine against the Zika virus linked to brain damage in babies. (AP Photo/Andre Penner)
A specialist fumigates the Nueva Esperanza graveyard in the outskirts of Lima on January 15, 2016. Health officials fumigated the largest cementery in Peru and second largest in the world to prevent Chikunguya and Zika virus, which affect several South American countries. AFP PHOTO/ERNESTO BENAVIDES / AFP / ERNESTO BENAVIDES (Photo credit should read ERNESTO BENAVIDES/AFP/Getty Images)
A specialist fumigates the Nueva Esperanza graveyard in the outskirts of Lima on January 15, 2016. Health officials fumigated the largest cemetery in Peru and second largest in the world to prevent Chikunguya and Zika virus, which affect several South American countries. AFP PHOTO/ERNESTO BENAVIDES / AFP / ERNESTO BENAVIDES (Photo credit should read ERNESTO BENAVIDES/AFP/Getty Images)
View of the Nueva Esperanza graveyard as it is fumigated in the outskirts of Lima on January 15, 2016. Health officials fumigated the largest cemetery in Peru and second largest in the world to prevent Chikunguya and Zika virus, which affect several South American countries. AFP PHOTO/ERNESTO BENAVIDES / AFP / ERNESTO BENAVIDES (Photo credit should read ERNESTO BENAVIDES/AFP/Getty Images)
A specialist fumigates the Nueva Esperanza graveyard in the outskirts of Lima on January 15, 2016. Health officials fumigated the largest cemetery in Peru and second largest in the world to prevent Chikunguya and Zika virus, which affect several South American countries. AFP PHOTO/ERNESTO BENAVIDES / AFP / ERNESTO BENAVIDES (Photo credit should read ERNESTO BENAVIDES/AFP/Getty Images)
A specialist fumigates the Nueva Esperanza graveyard in the outskirts of Lima on January 15, 2016. Health officials fumigated the largest cemetery in Peru and second largest in the world to prevent Chikunguya and Zika virus, which affect several South American countries. AFP PHOTO/ERNESTO BENAVIDES / AFP / ERNESTO BENAVIDES (Photo credit should read ERNESTO BENAVIDES/AFP/Getty Images)
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A tricky bug

The Zika virus is primarily transmitted by Aedes aegypti, the type of mosquito responsible for spreading dengue, yellow fever, and a whole host of other tropical infectious diseases. The mosquitoes pick up the virus from infected people, according to the US Centers for Disease Control and Prevention. Originally identified in 1947 in Uganda, Zika was relatively unknown until 2007, when there was an outbreak of the virus in Micronesia.

To treat these diseases, scientists have started looking into how to stop the mosquitoes. One step affected areas can try is introducing sterile mosquitoes into the area so as to curb their populations and prevent the disease from spreading. In the past, researchers have done this by zapping the bugs with radiation. Unfortunately, that strategy can also make the mosquitoes less competitive and more resistant to mating. So Oxitec tried a different approach: genetically modifying male mosquitoes, which in turn seek out female mosquitoes and mate with them, resulting in no offspring — and eventually, a size ably smaller mosquito population, if all goes well.

"They do what they want to do, which is seek out those females," Chris Creese, a spokeswoman for Oxitec told Business Insider. "That's why it's so effective." Creese said they've seen more than 90% suppression in trials of their genetically engineered mosquitoes.

Creese said Oxitec is planning on building out its project in Piracicaba, Brazil, an area that's particularly hard hit by viruses stemming from the Aedes aegypti mosquito. Right now, Oxitec's mosquitoes are able to cover about 5,000 people in a district of the city, but the company plans to spread the mosquitoes to cover the up-to-60,000-person urban center soon. Longer term, Oxitec said it's going to be able to scale out to cover about 300,000 people.

Mosquito Zika virusAP Photo/Felipe Dana

An untreatable virus

Until 2014, the virus had broken out only in Africa, Southeast Asia, and the Pacific Islands. That year, it spread to South America. By last May, Zika had made its way to Brazil. In the past year, Brazil has seen more than 84,000 cases of the virus. Only about one in five of those who are infected show symptoms, which most commonly include fever, rash, joint pain, and red eyes.

In total for 2015, thousands of babies — about 10 times the normal amount for a year — were born with microcephaly, a condition in which the brain is abnormally small. This birth defect was often found after the mother had Zika virus-like symptoms early in the pregnancy.

So far, there are no vaccines or treatments for Zika. The only way to prevent the infection is to avoid being bitten by mosquitoes. That's why the US government have been advising travelers who are pregnant or trying to get pregnant to avoid areas with an ongoing outbreak. Governments in areas where the outbreaks are happening are even advising women to postpone their plans to get pregnant.

"The advice from authorities in Brazil, Jamaica, and the Dominican Republic, to delay getting pregnant is definitely not a long-term solution," Creese said. "The World Health Organization recommends controlling the mosquito."

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