Unless she was upset with Manson for doing a bad Cuban accent, we can only assume she was referring to a cocaine problem.
More Rose and Manson:
Rose McGowan, Marilyn Manson
Rose McGowan reveals why she dumped Marilyn Manson
Rose McGowan arrives at the LA Premiere Of "DIOR & I" held at the Leo S. Bing Theatre on Wednesday, April 15, 2015, in Los Angeles. (Photo by Richard Shotwell/Invision/AP)
Alternative rock performer Marilyn Manson, left, arrives at the "Alien Resurrection" premiere with actress Rose McGowan and bandmate Twiggy, Thursday, Nov. 20, 1997, in the Westwood section of Los Angeles. (AP Photo/Chris Pizzello)
Marilyn Manson, right, poses with Rose McGowan as they arrive at the premiere of "Sleepy Hollow", Nov. 17, 1999, in Los Angeles. The film stars Christina Ricci and Johnny Depp. (AP Photo/Mark J. Terrill)
HOLLYWOOD, : US rock star Marilyn Manson (R) arrives at the premiere of Tim Burton's new film 'Sleepy Hollow' with his partner Rose McGowan (L), in Hollywood, 17 November 1999. The film is a Gothic thriller based on the Washington Irving novel. AFP PHOTO Lucy NICHOLSON (Photo credit should read LUCY NICHOLSON/AFP/Getty Images)
Marilyn Manson and Rose McGowan (Photo by Ke.Mazur/WireImage)
Rose McGowan and Marilyn Manson during Premiere of Paramount Pictures' 'Sleepy Hollow' at Mann Chinese Theatre in Hollywood, California, United States. (Photo by Ron Galella/WireImage)
NEW YORK, NY - JUNE 24: Director Rose McGowan takes part in the Q & A during the 'Dawn' New York screening and Q & A at the Elinor Bunin Munroe Film Center on June 24, 2015 in New York City. (Photo by Michael Loccisano/Getty Images)
NEW YORK, NY - JUNE 17: Actress Rose McGowan attends the Casa Reale Fine Jewelry Launch at The Box on June 17, 2015 in New York City. (Photo by Cindy Ord/Getty Images for Casa Reale)
LOS ANGELES, CA - DECEMBER 17: Rose McGowan at a voice over recording session for Call of Duty: Advanced Warfares 'Exo Zombies' mode, part of the Havoc DLC pack on December 17, 2014 in Los Angeles, California. (Photo by Rachel Murray/Getty Images for Activision)
Actress Rose McGowan attends amfARs fifth annual Inspiration Gala in Los Angeles, October 29, 2014 at Milk Studios in Hollywood, California. AFP PHOTO / ROBYN BECK (Photo credit should read ROBYN BECK/AFP/Getty Images)
HOLLYWOOD, CA - OCTOBER 21: Actress Rose McGowan attends the premiere of 'White Bird In A Blizzard' at ArcLight Hollywood on October 21, 2014 in Hollywood, California. (Photo by Jason Kempin/Getty Images)
WASHINGTON, DC - MAY 03: Rose McGowan attends the 100th Annual White House Correspondents' Association Dinner at the Washington Hilton on May 3, 2014 in Washington, DC. (Photo by Dimitrios Kambouris/Getty Images)
LONDON, ENGLAND - APRIL 25: An Alternative View of director Rose McGowan as she attends the Film Maker Photo Call during the Sundance London Film and Music Festival 2014 at the O2 Arena on April 25, 2014 in London, England. (Photo by Tim P. Whitby/Getty Images for Sundance London)
PARK CITY, UT - JANUARY 17: Director and actress Rose McGowan poses for a portrait during the 2014 Sundance Film Festival at the Getty Images Portrait Studio at the Village At The Lift Presented By McDonald's McCafe on January 17, 2014 in Park City, Utah. (Photo by Larry Busacca/Getty Images) Winter sports gear courtesy of Destination Sports & Adventures, Park City. (Photo by Larry Busacca/Getty Images)
LOS ANGELES, CA - JANUARY 11: Actress Rose McGowan attends The Art of Elysium's 7th Annual HEAVEN Gala presented by Mercedes-Benz at Skirball Cultural Center on January 11, 2014 in Los Angeles, California. (Photo by Mike Windle/Getty Images for Art of Elysium)
Discover More Like This
BACK TO SLIDE
McGowan and Manson were engaged for two years before calling it quits in 2001.
Back then, they attributed the split to "lifestyle differences." Now we know what those differences were.
She talked with host Andy Cohen about the devastating toll the drugs had on their relationship.
"Well it's one thing to party now and then, but when it becomes like a full time it's just ... I'm too busy," Rose explained.
At least they both turned out okay following the breakup.
He continued putting out his shock rock albums, and she moved behind the camera, directing her first short film titled "Dawn."