What's better than going into business with your bestie? George Clooney, Rande Gerber and Mike Meldman are the proud founders of Casamigos tequila, which was born after one too many tequila-filled nights at their homes in Mexico. “Our idea was to make the best-tasting, smoothest tequila around. So we did," Clooney and Gerber say on their website.
Drew Barrymore: Winemaker Woman
Drew Barrymore has come a long way since "E.T." and after her out of this world movie roles, she's embarked on a more earthy adventure: Winemaking! The stunning star teamed up with local Monterey, California winery, Carmel Road to create Barrymore by Carmel Road Pinot Grigio. A fan of bright, crisp white wines, Barrymore’s first offering for Carmel Road is a Pinot Grigio, which is a bright, crisp white wine with flavors of lemon drop, Asian pear and honeydew melon star.
Jimmy Buffett: The Margarita Man
Why wouldn't you want to waste away in Margaritaville? Jimmy Buffett coined the lifestyle that embodies Margaritaville after an inspired trip to Key West in the late 1960s. His brand now has several tequilas, rums, Landshark Lager, and of course, plenty of themed restaurants.
Brad Pitt and Angelina Jolie: Royal Winos
Is there anything that Brad Pitt and Angelina Jolie don't do? The power couple have been enjoying a laid back life at Château Miraval, a 1,200-acre estate in the village of Correns, France, that they have called home since 2008 and have clearly gotten used to the region's industry of choice: Winemaking. The duo released a Château Miraval Rose in 2013 that got quite a bit of praise.
(Photo by Jon Kopaloff/FilmMagic)
Justin Timberlake: Hospitality Hottie
J.T. loves his tequila! In 2014, Justin Timberlake created a brand of Sauza Tequila called "901" – the name is inspired by his hometown area code in Memphis and "the time of night things start to get interesting." So there's that. Timberlake also owns several restaurants.
Photo: D Dipasupil via Getty Images
Sean 'Diddy' Combs: Beverage Tycoon
Off the stage, Sean 'Diddy' Combs is making a name for himself in the booze business. In 2014, the music mogul got into a joint venture with spirits giant Diageo to expand DeLeón Tequila. The newly expanded DeLeón portfolio boasts six ultra-premium and luxury expressions and sells for $60 - $850.
Diddy has also been partnered with premium Diageo brand CÎROC® Ultra Premium Vodka since 2007. CÎROC is like all brands in the Combs Wine & Spirits portfolio, its about quality and luxury. CÎROC pairs the finest ingredients with a grassroots marketing approach to deliver great experiences for their audience.
Bethenny Frankel: The Original Skinnygirl
Long before low-cal beverages hit the market, "Real Housewives of New York" star Bethenny Frankel was blending up low-cal margaritas for her gal pals. The business-savvy star achieved record success with her Skinnygirl Margarita and eventually sold her entire Skinnygirl® Cocktails brand to powerhouse Beam Inc., in March 2011.
Kenny Chesney: Rum Runner
Like Jimmy Buffett, country superstar Kenny Chesney also enjoys a low-key lifestyle in the Florida Keys. The chart-topper attempted to bottle the island vibe with a premium blended-rum brand, Blue Chair Bay, aptly named after his classic song "The Old Blue Chair."
(Photo by Christopher Polk/Getty Images for dcp)
Hanson: Quippy Beer Enthusiasts
Who knew that Hanson enjoyed microbrews? The recording artists/brothers Issac Hanson, Taylor Hanson and Zac Hanson of Hanson created their very own brand of beer, cleverly named… "Mmmhops!" If you don't understand the name, we can't be friends anymore.
(Photo by David Livingston/Getty Images)
Stephen Amell: Undercover Winemaker
Stephen Amell plays The Arrow in the hit CW series of the same name, but off-screen he prefers to kick back at his winery in Walla Walla, Washington. The actor embarked in a winemaking adventure with his pal Andrew Harding in 2012 and the duo are now the proud owners of Nocking Point Winery. (Photo by David Livingston/Getty Images)
Dan Akroyd: Grape Guru
Dan Akroyd is a serious winemaker! The veteran thespian has been churning out blends for over a decade and is the man behind Diamond Estates Winery.
(Photo by Rick Eglinton/Toronto Star via Getty Images)
Fergie: Vodka Connoisseur
Fergie apparently loves a good cocktail, but she doesn't love the calories. Enter Voli Vodka -- a guilt-free, low-cal line of vodkas that comes in six different flavors and was started by the Black Eyed Peas frontwoman in 2012.
(AP Photo/Evan Agostini)
Antonio Bandera: Vine Lover
Another man with a love of the vine? Antonio Banderas! The Spanish superstar is a partner at Anta Banderas Winery, which he's been working with since 1999.
(Photo by Gustavo Caballero/Getty Images)
Vince Neil: Rockin' Booze Boss
Vince Neil is the legendary lead singer of Motley Crue, but off the stage he is a spirits enthusiast. The rock god owns The Tatuado Brand, which boasts spirits, vodka, tequila, rum, and his dynamic portfolio of restaurants.
(Photo by Kevin Mazur/WireImage)
Willie Nelson: Whiskey Musician
No surprise here! Willie Nelson's whiskey has a musical addition. Nelson is the the man behind Old Whiskey River bourbon and each bottle of the Kentucky-made liquor comes with a guitar pick. This could be good if you're feeling inspired post-buzz. (Photo by Lester Cohen/WireImage)
Marilyn Manson: Absinthe Ace
Did you know Marilyn Manson had a spirits brand? The goth rocker is the proud owner of Mansinthe, his own brand of Swiss-made absinthe. The beverage won a gold medal at the 2008 San Francisco World Spirits Competition.
Avión Tequila: The Entourage's Drink of Choice
While the boys of "Entourage" are not the owners of tequila brand, Avión, the bottle is know as the "Entourage Tequila." "Entourage" creator Doug Ellin is an investor in the small batch, ultra-premium tequila. If you weren't convinced, all you need is this funny photo from the set of the upcoming movie. Mark Cuban and Jerry Ferrara aka Turtle seem to be happy to have Avión on tap.
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Booze is a big business, which is why it is no surprise that plenty of celebs have tapped into the spirits market either as a fun pastime or a serious entrepreneurial adventure.
Since today happens to be one of the biggest drinking holidays of the year -- St. Patrick's Day -- we've rounded up 17 of the biggest names in the booze business. Check it out in the gallery above!