Peyton Manning throws 500th career TD pass

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Peyton Manning throws 500th career TD pass
Denver Broncos quarterback Peyton Manning talks to the media after working out at the NFL football teams training facility in Englewood, Colo., on Monday, April 21, 2014. (AP Photo/Ed Andrieski)
EAST RUTHERFORD, NJ - AUGUST 09: Quarterback Eli Manning #10 of the New York Giants meets with quarterback Bruce Gradkowski #5 of the Pittsburgh Steelers following a preseason game at MetLife Stadium on August 9, 2014 in East Rutherford, New Jersey. (Photo by Elsa/Getty Images)
Denver Broncos quarterback Peyton Manning talks to the media after working out at the NFL football teams training facility in Englewood, Colo., on Monday, April 21, 2014. (AP Photo/Ed Andrieski)
NEW YORK, NY - JUNE 11: New York Giants' quarterback Eli Manning (C) and guests celebrate Father's Day at Studio Arte on June 11, 2014 in New York City. (Photo by Slaven Vlasic/Getty Images)
In this photo provided by the Denver Broncos, quarterback Peyton Manning, right, and other offensive players work during the first phase of the offseason training program at the NFL football teams training facility in Englewood, Colo., on Monday, April 21, 2014. (AP Photo/Denver Broncos, Eric Lars Bakke)
EAST RUTHERFORD, NJ - FEBRUARY 02: Quarterback Peyton Manning #18 of the Denver Broncos looks to pass against the Seattle Seahawks during Super Bowl XLVIII at MetLife Stadium on February 2, 2014 in East Rutherford, New Jersey. (Photo by Kevin C. Cox/Getty Images)
NEW YORK, NY - JUNE 11: New York Giants' quarterback Eli Manning celebrates Father's Day at Studio Arte on June 11, 2014 in New York City. (Photo by Slaven Vlasic/Getty Images)
EAST RUTHERFORD, NJ - FEBRUARY 02: Quarterback Peyton Manning #18 of the Denver Broncos looks to pass against the Seattle Seahawks during Super Bowl XLVIII at MetLife Stadium on February 2, 2014 in East Rutherford, New Jersey. (Photo by Jeff Gross/Getty Images)
NEW YORK, NY - FEBRUARY 01: Actor Tracy Morgan (L) and NFL player Eli Manning attend the DirecTV Beach Bowl at Pier 40 on February 1, 2014 in New York City. (Photo by Kevin Mazur/Getty Images for DirecTV)
EAST RUTHERFORD, NJ - FEBRUARY 02: Quarterback Peyton Manning #18 of the Denver Broncos looks to pass against the Seattle Seahawks during Super Bowl XLVIII at MetLife Stadium on February 2, 2014 in East Rutherford, New Jersey. (Photo by Kevin C. Cox/Getty Images)
New York Giants quarterback Eli Manning (10) throws against the Pittsburgh Steelers in the first quarter of a preseason NFL football game, Saturday, Aug. 9, 2014, in East Rutherford, N.J. (AP Photo/Frank Franklin II)
EAST RUTHERFORD, NJ - FEBRUARY 02: Quarterback Peyton Manning #18 of the Denver Broncos looks on from the bench in the third quarter against the Seattle Seahawks during Super Bowl XLVIII at MetLife Stadium on February 2, 2014 in East Rutherford, New Jersey. (Photo by Kevin C. Cox/Getty Images)
EAST RUTHERFORD, NJ - FEBRUARY 02: Quarterback Peyton Manning #18 of the Denver Broncos warms-up before playing against the Seattle Seahawks during Super Bowl XLVIII at MetLife Stadium on February 2, 2014 in East Rutherford, New Jersey. (Photo by Kevin C. Cox/Getty Images)
NEW YORK, NY - MAY 04: Eli Manning of the New York Giants and Peyton Manning of the Denver Broncos appear at the game between the New York Yankees and the Tampa Bay Rays on May 4, 2014 in the Bronx borough of New York City. (Photo by Al Bello/Getty Images)
PEBBLE BEACH, CA - FEBRUARY 07: Denver Broncos quarterback Peyton Manning looks on from the 14th hole tee box during the second round of the AT&T Pebble Beach National Pro-Am at the Pebble Beach Golf Links on February 7, 2014 in Pebble Beach, California. (Photo by Christian Petersen/Getty Images)
NEW YORK, NY - MAY 07: Eli Manning attends the Pittsburgh Penguins verse New York Rangers playoff game at Madison Square Garden on May 7, 2014 in New York City. (Photo by James Devaney/GC Images)
PEBBLE BEACH, CA - FEBRUARY 07: Denver Broncos quarterback Peyton Manning hits a tee shot on the 14th hole during the second round of the AT&T Pebble Beach National Pro-Am at the Pebble Beach Golf Links on February 7, 2014 in Pebble Beach, California. (Photo by Christian Petersen/Getty Images)
NEW YORK, NY - JUNE 11: (L-R) 'FOX & Friends' co-hosts Elisabeth Hasselbeck and Brian Kilmeade talk to New York Giants' quarterback Eli Manning at 'FOX & Friends' outside of FOX Studios on June 11, 2014 in New York City. (Photo by Slaven Vlasic/Getty Images)
PEBBLE BEACH, CA - FEBRUARY 05: (L-R) Denver Broncos quarterback, Peyton Manning watches a tee shot from New England Patriots head coach, Bill Belichick on the third hole during a practice round for the AT&T Pebble Beach National Pro-Am at Pebble Beach Golf Links on February 5, 2014 in Pebble Beach, California. (Photo by Christian Petersen/Getty Images)
NEW YORK, NY - MAY 12: Eli Manning is seen on May 12, 2014 in New York City. (Photo by Demis Maryannakis/Star Max/GC Images)
PEBBLE BEACH, CA - FEBRUARY 05: Denver Broncos quarterback, Peyton Manning hits a tee shot on the second hole during a practice round for the AT&T Pebble Beach National Pro-Am at Pebble Beach Golf Links on February 5, 2014 in Pebble Beach, California. (Photo by Christian Petersen/Getty Images)
NEW YORK, NY - FEBRUARY 01: Eli Manning and Serena Williams attend the DirecTV Beach Bowl at Pier 40 on February 1, 2014 in New York City. (Photo by Theo Wargo/Getty Images for DirecTV)
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By ARNIE STAPLETON

DENVER (AP) -- Peyton Manning joined Brett Favre in the NFL's most exclusive of clubs with his 500th touchdown pass Sunday when the Denver Broncos handed the Arizona Cardinals their first loss, 41-20.

Manning finished with four TD throws, moving him within five of Favre's record 508.

Manning found tight end Julius Thomas twice in the end zone, including the touchstone touchdown, a 7-yard dart in the first quarter.

Yet, it was wide receiver Demaryius Thomas who had the biggest day for the Broncos (3-1) with eight catches for a team-record 226 yards and two TDs. That beat Shannon Sharpe's mark of 214 yards set against Kansas City in 2002.

Demaryius Thomas caught touchdown passes of 31 and 86 yards - and his 77-yard TD was nullified by left tackle Ryan Clady's chop block in the third quarter. Arizona (3-1) lost for the first time and saw quarterback Drew Stanton leave with a possible concussion.

Manning finished 31 of 47 for 479 yards, four TDs and two interceptions. Emmanuel Sanders caught seven passes for 101 yards.

Stanton, subbing for Carson Palmer again, was knocked from the game on a hard hit by Von Miller in the third period and Logan Thomas came in for Arizona (3-1). Stanton finished 11 of 26 for 118 yards.

After getting sacked twice on his first drive and throwing two incompletions on his second, Thomas threaded a pass through linebacker Nate Irving's grasp. It landed in the arms of running back Andre Ellington for a stunning 81-yard score that made it 24-20 late in the third quarter.

That ended up being Thomas' only completion in eight attempts.

Brandon McManus, whose solid start convinced the Broncos that they should release the suspended Matt Prater, made it 27-20 when his 41-yard field goal bounced off the left post and through the uprights.

Earlier, McManus was good from 44 yards, but wide left from 53.

Manning then threw his fourth TD and second to Julius Thomas, a 12-yarder that made it 34-20. It was the tight end's seventh TD grab of the season.

With Montee Ball sidelined with a groin injury, Ronnie Hillman ran for 64 yards on 14 carries. Rookie Juwan Thompson bullied his way in from 8 yards to cap the scoring.

Broncos linebacker Danny Trevathan made his 2014 debut after breaking his left leg in the preseason. He led the Broncos with seven tackles, six solo.

Manning's 500th TD throw came in his 244th career regular season game, 49 fewer games than it took Favre. It came against two of his mentors: Arizona coach Bruce Arians and Cardinals assistant head coach Tom Moore. Arians was Manning's first position coach in 1998 and Moore was his offensive coordinator during his entire time in Indy.

Knowing him better than any other team does, it wasn't surprising the Cardinals came up with two interceptions of Manning, either. What was a big surprise was 300-pound defensive end Calais Campbell snatching Manning's screen pass and rumbling to the 5, where Manning tripped him up. Ellington took it in from there to pull Arizona to 14-13.

Campbell later left with a right knee injury.

Manning had his own quick score up his sleeve. He saw cornerback Antonio Cromartie lined up 1 on 1 on Demaryius Thomas. Manning hit his big receiver in stride at the 40 and Thomas sped into the end zone with an 86-yard score that gave Denver a 21-13 halftime lead.

On the final play of the first half, Broncos slot receiver Wes Welker broke Rod Smith's mark for most catches by an undrafted player. His 850th career grab, his third of the game, covered 5 yards.

Peyton Manning Throws 500th TD Pass

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