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Group of rare children may be key to new vaccine

Children With Rare Malaria Immunity Could Mean New Vaccine

Scientists say they have found an unlikely new weapon in the fight against malaria - a group of children in Tanzania.

BBC reports: "Malaria is rife there, and yet researchers found a group of children who seem naturally resistant to the disease, and their antibodies could be used in a vaccine."

After analyzing blood samples from 1,000 Tanzanian toddlers, the journal Science says researchers from Brown University's medical school discovered 6 percent of those children produce an antibody that attacks the malaria-causing parasite and makes the children immune to the disease.

Scientists say these unique antibodies essentially trap the malaria parasite in red blood cells during a key stage in its life cycle. This prevents the parasite from bursting out and spreading throughout the host's body.

The research team's spokesperson told Forbes: "Most vaccine candidates for malaria have worked by trying to prevent parasites from entering red blood cells. We've taken a different approach. ...We're sort of trapping the parasite in the burning house."

Encouraged by this remarkable find, the researchers then injected a form of the antibody into mice. They discovered the animals were also suddenly protected from the disease. (Via YouTube / VideoProtocols Com)

The study's lead author told the BBC these antibodies could potentially become a new vaccine, and he's encouraged by the results. "I am cautious. I've seen nothing so far in our data that would cause us to lose enthusiasm. However, it still needs to get through a monkey study and the next phase of human trials."

But if the antibodies pass the remaining tests, they could have a huge impact on the world of medicine.

According to the World Health Organization, an estimated 627,000 people die from malaria every year. A new vaccine that stops the disease from spreading inside the body could save many of those lives.

The study was published in the journal Science Friday.

Join the discussion

1000|Char. 1000  Char.
Bill May 26 2014 at 9:05 AM

Without humans to work with, little progress can be made to control or erradicate major diseases. I'm proiud to be a "polio pioneer" for the trial runs of the Salk vaccine against polio. You can thank me and others who volunteered for this.

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5 replies
kingofswords72 May 23 2014 at 8:31 PM

It's amazing how scientists are working around the clock on vaccines and other life saving strategies while behind the scenes the eugenics advocates are looking for new ways to eliminate the masses.

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5 replies
abyfrost May 26 2014 at 6:04 AM

1,000 KIDS (CHILDREN) how did they get their blood samples & 60 of those KIDS
(CHIIDREN) have this resistance WHO IS WATCHING OUT for them to make sure they are not the lab rats or the mice?

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6 replies
ltjaysantos May 26 2014 at 7:42 AM

These scientists should stop trying to play God with these poor black children.

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9 replies
iliayana May 23 2014 at 6:39 PM

please keep working on this

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lgre470640 May 26 2014 at 12:11 PM

Well , I hope at least they get the permission to do research on the children, and treat any after affects. The govt doesn't need another Tuskeege Experiment on their hands. Injecting black share croppers back in the early 30's, with Syphillis and not treating or telling them what they did .

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2 replies
calderasf lgre470640 May 26 2014 at 1:18 PM

Yeah lets make stupid comments it's 80 years into the future

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1 reply
SemperFidelis calderasf May 26 2014 at 8:37 PM

Lets see they injected our military with anthrax without our knowledge. We were used as guinea pigs. Sure there are other injections we were shot with also that hasn't made it to public knowledge. To think our government has our best intentions is what a dumb 18 year old thought also back during the first Desert Storm.

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eltrip lgre470640 May 26 2014 at 1:38 PM

Are you just trying to demonstrate your knowledge of Tuskegee or do you really see a comparison between these 2 unrelated things?

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1 reply
klw4919 eltrip May 26 2014 at 7:47 PM

You have to keep in mind this generation of paranioid racebaters see racism in everything.This is what they are taught in school and at hope. It is a hopeless situation. I'm surprised someone isn't saying that the white man brought malaria to Africa.

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alfredschrader May 26 2014 at 10:11 AM

Geo: DDT actually increases the problem because mosquito eaters die when they ingest the DDT. Esp. spiders, bats, and finches.

Mosquitos can be linked back to the algae that feeds the mosquito larve.
The algae need nitrates which the moquitos aquire and bring back to the algae.
Kill the algae, and stop the mosquitos.

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3 replies
LA is Best May 26 2014 at 9:12 AM

Mosquitos could be controlled by using harmless DDT! Of course it harder to control people when they are healthy!

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3 replies
Normie Baby May 26 2014 at 11:04 AM

Such wonderful news. Science may have finally found a way to counter the effect of Rachael Carson and all of her stupid followers, finally. It's too late for the 60 million she has already killed, but it is wonderful news, never the less.

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1 reply
capeschk Normie Baby May 26 2014 at 6:18 PM

Invented numbers and hyperbole don't make an argument. Address your neuroses first.

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1 reply
klw4919 capeschk May 26 2014 at 7:56 PM

It's so amusing to see leftists actiing so true to form and type. You are always diagnosing people who don't agree with you as mentally ill.It's either that or attack their intelligence because after all, people like you really are more intelligent than the masses, aren't you? It's right out of the Soviet playbook. Of course, you still miss that workers' paradise, don't you?

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calderasf May 26 2014 at 1:14 PM

Good for the human race our immune system is awesome.

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1 reply
meepstein calderasf May 26 2014 at 4:37 PM

But it still won't cure stupidity.

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1 reply
knarfdr meepstein May 26 2014 at 6:09 PM

Bingo!

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